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Abstract Objective The aims of the study were to evaluate, after pregnancy, the glycemic status of women with history of gestational diabetes mellitus (GDM) and to identify clinical variables associated with the develo...

Identification of key factors associated with the risk of developing cardiovascular disease and quantification of this risk using multivariable prediction algorithms are among the major advances made in preventive cardio...

Traditional measures for assessing the performance of classification models for binary outcomes are the ROC curve and the area under the ROC curve (AUC). Reclassification tables (Cook, 2008), net reclassification improv...

Abstract Accurate prediction of invasive mechanical ventilation (IMV) requirement in patients with community-acquired pneumonia (CAP) is a key clinical challenge. Conventional static risk stratification scores have limit...

BackgroundHigh-dose intravenous methylprednisolone (HD-IVMP) is the first-line treatment for dysthyroid optic neuropathy (DON). However, a significant proportion of patients exhibit a poor response, risking irreversible ...

Abstract Purpose Patients with nasopharyngeal carcinoma (NPC) exhibiting persistent EBV DNA positivity throughout treatment (a “D-D-D” trajectory) represent a high-risk group with undefined management strategies. Thi...

The study examines the grammatical concept of exception as articulated in Arabic and Spanish through various syntactic constructions. This study is driven by the growing need to address structural asymmetries in bilingua...

Key Points. Lower maternal midterm eGFR was independently associated with increased risks of low birth weight and small for gestational age. Adding eGFR to conventional risk models improved prediction of adverse birth ou...

Abstract Background Both the atherogenic index of plasma (AIP) and obesity have been implicated in cardiovascular disease (CVD) risk. This study aimed to investigate the associations of AIP and AIP-obesity indices (AIP-W...

ABSTRACT Cysteine proteases are hydrolases that share a common catalytic mechanism involving a nucleophilic cysteine thiol in a catalytic dyad or triad. Here, we review the current clans that make up the cysteine proteas...

IntroductionHyperinflammatory and hemophagocytic lymphohistiocytosis (HLH)-like presentations are increasingly recognized as clinical “red flags” for inborn errors of immunity (IEI), including severe combined immunod...

Abstract Background Antenatal hydronephrosis (AHN) is a common urological abnormality identified during prenatal ultrasound examination, with heterogeneous underlying causes. This study aimed to investigate the genetic e...

Background and aims The Heavy, Hypertensive, Atrial fibrillation, Pulmonary hypertension, Elder, Filling pressure (H2FPEF) score is a widely used diagnostic tool for heart failure with preserved ejection fraction (HFpEF)...

Abstract Background Visceral obesity contributes to hypertension through pathways of insulin resistance and inflammation. The joint association of C-reactive protein-triglyceride-glucose index (CTI), which integrates the...

BackgroundGlucocorticoid therapy in pneumonia patients confounds conventional inflammatory biomarkers, hindering accurate risk stratification. The lactate dehydrogenase-to-albumin ratio (LAR), a proposed steroid-resilien...

Aim: Chronic liver disease (CLD) is characterized by progressive impairment of hepatic function and frequent lipid metabolism abnormalities, with reductions in high-density lipoprotein cholesterol (HDL-C) and other lipop...

PurposeThis study aimed to investigate the associations between gut metabolites Trimethylamine N-Oxide (TMAO), the novel platelet-derived inflammatory ratio index neutrophil-to-platelet ratio (NPR), and the prognosis of ...

The classification of Chinese phrase structures has traditionally been based on formal configuration, especially categories such as subject-predicate, verb-object, and modifier-head constructions. Although this approach ...

The objective of this study was to evaluate the genotype-environment interaction (GEI) in the body weight adjusted to 550 days of age (W550) of Polled Nellore cattle raised in Northeastern Brazil using reaction norms (RN...

Este artículo aborda el debate planteado por Archer respecto a las postulaciones de Giddens sobre las relaciones globales y la reflexividad. Esa discusión se configura a partir de la reclasificación sociológica que r...

Abstract Background The role of leukocyte telomere length (LTL) in predicting lung cancer risk remains controversial, particularly in individuals with pulmonary nodules. Methods We conducted a prospective cohort study of...

Abstract Background Discordance between small dense low-density lipoprotein cholesterol (sdLDL-C) and low-density lipoprotein cholesterol (LDL-C) levels is common. Whether this easily calculated parameter, derived from r...

Abstract Objective This study aimed to investigate the independent predictive value of the uric acid-to-HDL-C ratio (UHR) for metabolic syndrome (MS) in the elderly, develop an optimized diagnostic model, and assess whet...

Xiaoying Wang,1,* Yuanyuan Ning,2,* Xiaojuan Wang,1 Guangli Li,1 Dong Wu,1 Xiaowu Wang,3 Zhen Huang4 1Department of Pharmacy, Fuyang People’s Hospital, Fuyang, Anhui, 236000, People’s Republic of Chin...