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A dual-mechanism model of Selinexor in DLBCL: p53 reactivation and metabolic reprogramming
Article
Article
Wenqi Zhang et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy with limited therapeutic options in the relapsed or refractory setting. Selinexor, a selective inhibitor of nuclear export targeting X...
LCC LCC:MedicineIdioma English
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Open Access
ANALYSING THE LEGAL AND INSTITUTIONAL FRAMEWORK GOVERNING THE ESTABLISHMENT OF A NUCLEAR POWER PLANT IN KENYA
Article
Article
Hannah Wamuyu · Nomos Verlagsgesellschaft mbH & Co. KG · 2026 · ISSN 2363-6262
The article examines the legal and institutional framework governing the establishment of nuclear power program in Kenya owing to the heightened efforts by the government in laying out the plans to establish the first nu...
LCC TENDOkxhdw~~Idioma English
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O projeto do submarino nuclear brasileiro The Brazilian nuclear submarine project
Article
Article
João Roberto Martins Filho · Pontifícia Universidade Católica do Rio de Janeiro, Instituto de Relações Internacionais · 2011 · ISSN 0102-8529
O artigo procura reconstruir a trajetória do programa do submarino nuclear brasileiro desde suas origens, no governo Geisel, aos dias atuais. Lançando mão do conceito de oportunismo tecnológico, procura analisar a at...
LCC LCC:International relationsIdioma English
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Open Access
Optimization of 1D 1H Quantitative NMR (Nuclear Magnetic Resonance) Conditions for Polar Metabolites in Meat
Article
Article
Hyun Cheol Kim et al · Springer Nature · 2019 · ISSN 2636-0772
Abstract The objective of this study was to establish an optimized 1D 1H quantitative nuclear magnetic resonance (qNMR) analytical method for analyzing polar metabolites in meat. Three extraction solutions [0.6 M perchlo...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma English
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Material complementario
Sex-specific KDM6A-HNF4A-CREBH network controls lipoprotein cholesterol metabolism and atherosclerosis via epigenetic reprograming of hepatocytes
Article
Article
Lin Chen et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract The liver is a central organ controlling lipid and cholesterol metabolism and plays a key role in regulating lipoprotein profiles and cardiovascular disease risk. Males and females show clear differences in chol...
LCC TENDOlNjaWVuY2U~Idioma English
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Open Access
Iran Talks: Das Palavras aos Atos. A Declaração de Teerã e o Plano de Ação Conjunto de Genebra em Perspectiva
Article
Article
Antonio Jorge Ramalho da Rocha et al · Pontifícia Universidade Católica do Rio de Janeiro, Instituto de Relações Internacionais · 2014 · ISSN 1982-0240
Este artigo analisa a Declaração de Teerã, de 2010, e o Plano de Ação Conjunto de Genebra, de 2013. Ao examinar as razões que explicam por que esses dois processos negociadores sobre o programa nuclear iraniano alc...
LCC LCC:International relationsIdioma English
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Open Access
Study of Using Virtual Reality Technology to Simulate the Generation of Electrical Power from Different Sources
Article
Article
Aous Naji Rasheed et al · Tikrit University · 2026 · ISSN 1813-162X
Virtual reality (VR) is one of the most common technologies nowadays, which make a virtual environment exactly similar to the real environment. The purpose behind this is to test several issues (designing or manufacturin...
LCC LCC:Engineering (General). Civil engineering (General)Idioma English
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Open Access
An electrospun polymer composite with fullerene-multiwalled carbon nanotube exohedral complexes can act as memory device
Article
Article
Molinari, Fabricio Nicolás et al · Elsevier · 2020 · ISSN 0032-3861
Functional polymer nanocomposites with distinctive electrical properties made of nanocarbon structures and biodegradable polymers are promising materials for the development of flexible and eco-friendly smart systems. In...
Idioma English
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Attitude and Involvement Regarding Sexual and Reproductive Health Among University Students: A Cross‐Sectional Study in Bangladesh
Article
Article
Ishita Akhter et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Sexual and reproductive health (SRH) is a crucial aspect of overall health and well‐being, especially among young adults. However, in many low‐ and middle‐income countries, including Ba...
LCC LCC:MedicineIdioma English
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Material complementario
Calculating Energy Levels of 48Cr using Skyrme (SLY5) Interactions
Article
Article
Sarah Darweesh et al · University of Mosul, College of Education for Pure Science · 2024 · ISSN 1812-125X
In this paper, we obtained the nuclear energy levels for 48Cr isotope that resided in the pf -shell of shell model calculations. For nucleons that were outside closed and no core, they were calculated using skyrme intera...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma English
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Open Access
Caracterización genética de razas de maíz autóctonas de Misiones, Argentina
Article
Article
Bracco, Mariana et al · Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Quí­micas y Naturales. Centro de Investigación y Desarrollo Tecnológico · 2013 · ISSN 0329-8922
En el norte de la Argentina habitan comunidades aborígenes Guaraníes que cultivan razas nativas de maíz. La caracterización genética del germoplasma autóctono, en particular de las razas de la Provincia de Misiones...
Idioma Spanish
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Open Access
Characterization of the BPC genes in alfalfa and functional verification of MsBPC10 in salt tolerance
Article
Article
Li Zhao et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Soil salinization severely restricts the growth and forage yield of Medicago sativa (alfalfa), a globally critical leguminous forage crop, yet the regulatory mechanisms governing its salt tolerance re...
LCC TENDOkJvdGFueQ~~Idioma English
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Open Access
DDX5 orchestrates RNA homeostasis to ensure oocyte developmental competence
Article
Article
Mengting Wang et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Oocyte development requires tight regulation of transcription and RNA metabolism, which is coordinated by RNA-binding proteins, whose roles in mammalian oogenesis remain incompletely understood. Here, we identif...
LCC TENDOlNjaWVuY2U~Idioma English
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Open Access
Design and simulation of sun position sensors for space applications: A comparative study
Article
Article
Diaz Salazar, Martha et al · American Institute of Physics · 2024 · ISSN 0034-6748
Sun position sensors are used in space applications as part of the attitude determination and control system. The aim of this work is to describe the design process of single and dual axis sun position sensors based on a...
Idioma English
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Open Access
Efeito da hiperprolactinemia induzida pela metoclopramida na glândula lacrimal: estudo experimental Effects of metoclopramide-induced hyperprolactinemia on the lacrimal gland: experimental study
Article
Article
Carina Verna et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2005 · ISSN 0100-7203
OBJETIVO: avaliar as alterações morfológicas promovidas pela hiperprolactinemia induzida pela metoclopramida na glândula lacrimal de camundongas durante a fase de proestro e gestação. MÉTODOS: 40 camundongas adult...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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Estudo piloto dos efeitos da terapia hormonal sobre o tecido mamário normal de mulheres após a menopausa A pilot study of the effects of hormone therapy on normal breast tissue of postmenopausal women
Article
Article
Simone Elias et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2006 · ISSN 0100-7203
OBJETIVOS: avaliou-se o tecido mamário de mulheres antes e depois de seis meses de terapia estroprogestativa combinada contínua (0,625 mg de estrogênios conjugados eqüinos associados a 2,5 mg de acetato de medroxipro...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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Material complementario
Ethylbenzene production over platinum catalysts supported on modified KY zeolites
Article
Article
Fonseca, Juliana Da Silva Lima et al · Elsevier Science · 2010 · ISSN 0926-860X
Platinum catalysts supported on zeolite KY (Si/Al = 12.7), modified with magnesium, calcium or barium, were evaluated in n-octane reforming to produce ethylbenzene. The catalysts were characterized by nitrogen adsorption...
Idioma English
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Open Access
Extension of charge-state-distribution calculations for ion-solid collisions towards low velocities and many-electron ions
Article
Article
Lamour, E. et al · American Physical Society · 2015 · ISSN 1050-2947
Knowledge of the detailed evolution of the whole charge-state distribution of projectile ions colliding with targets is required in several fields of research such as material science and atomic and nuclear physics but a...
Idioma English
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Open Access
FLT3-SYK inhibitor and Ixazomib combination impact HOXA and oxidative stress control by β-catenin, SQSTM1 and NRF2 in AML
Article
Article
Santhosh Kumar Pasupuleti et al · Nature Portfolio · 2026 · ISSN 2397-768X
Abstract Acute myeloid leukemia (AML) is sustained by oncogenic signaling and stress-adaptive networks that enable proliferative sustenance and therapeutic resistance. Transcriptomic profiling of AML blasts revealed upre...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma English
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Material complementario
From the membrane to the nucleus: Mechanical signals and transcription regulation
Article
Article
Oses Oliveto, Camila Maite et al · Springer · 2023 · ISSN 1867-2450
Mechanical forces drive and modulate a wide variety of processes in eukaryotic cells including those occurring in the nucleus. Relevantly, forces are fundamental during development since they guide lineage specifications...
Idioma English
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Open Access
Investigate Oblique Incident Alpha Particle Tracks on CR-39 Detector
Article
Article
Yasser Khlile et al · University of Mosul, College of Education for Pure Science · 2020 · ISSN 1812-125X
In this paper, the nuclear track detector CR-39 with a thickness of 200 µm is divided to several pieces. The area of one piece is 1 x 1 cm2. This study has involved two parts. Fist part is without irradiated by alpha pa...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma English
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Open Access
Male sterility and somatic hybridization in plant breeding
Article
Article
Alejandro A. Edera et al · Facultad de Ciencias Agrarias. Universidad Nacional de Cuyo · 2019 · ISSN 0370-4661
Plant male sterility refers to the failure in the production of fertile pollen. It occurs spontaneously in natural populations and may be caused by genes encoded in the nuclear (genic male sterility; GMS) or mitochondria...
LCC LCC:Agriculture; TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~Idioma English
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Open Access
Morfologia dos cardiomiócitos e quantificação do colágeno no miocárdio de ratas tratadas com isoflavonas ou estrogênios Cardiomyocytes morphology and collagen quantification in the myocardium of female rats treated with isoflavones or estrogens
Article
Article
Luciana Alécio Cabanelas et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2012 · ISSN 0100-7203
OBJETIVOS: Avaliar a morfologia dos cardiomiócitos e quantificar o colágeno presente no miocárdio de ratas tratadas com extrato concentrado de soja ou 17β-estradiol (E2). MÉTODOS: Vinte e oito ratas foram dividi...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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Open Access
Oócitos aparentemente maduros injetados em telófase I apresentam piores resultados de reprodução assistida Apparently matured oocytes injected in telophase I have worse outcomes from assisted reproduction
Article
Article
Luciana Azôr Dib et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2012 · ISSN 0100-7203
OBJETIVO: Avaliar o estágio de maturação nuclear de oócitos com o primeiro corpúsculo polar (CP) visível de pacientes inférteis submetidas à estimulação ovariana para injeção intracitoplasmática de espermato...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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Open Access
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