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BackgroundX-linked hyper-IgM syndrome (XHIM) due to CD40L deficiency typically presents in early childhood with recurrent sinopulmonary or opportunistic infections, and its initial manifestations can be misleading. We re...

Background: Cervical Cancer is still a major public health challenge in low and middle-income countries. HPV testing has been an innovative approach, which was introduced in Argentina for women aged 30+ through the Jujuy...

Abstract Background Disparities in the utilization of essential medical products are a key factor contributing to inequality in health outcomes. We aimed to analyze the trends and influencing factors in using Coronavirus...

BackgroundEarly complement pathway deficiencies predispose to invasive infections with encapsulated bacteria. C2 deficiency is the most common human complement deficiency, yet it may remain clinically silent until a life...

OBJETIVOS: Verificar a cobertura, pelo teste de Papanicolaou, de idosas e os fatores associados. MÉTODOS: Foi desenvolvido um estudo de base populacional com inquérito domiciliar. Os critérios de inclusão foram mulhe...

Abstract Background This study was conducted to determine the seroprevalence of HIV among pregnant women in Brazil and to describe HIV testing coverage and the uptake of antenatal care (ANC). Methods Between October ...

Abstract Background Heart murmurs are detected commonly in apparently healthy cats during routine physical examination, and Doppler echocardiography ultimately is required to identify the source of flow turbulence causin...

IntroductionComplement C2 deficiency is a classical pathway defect associated with recurrent infections and autoimmunity. This case demonstrates the need for increased awareness amongst rheumatologists for the indication...

Objective To investigate the influence of water on the monotonic and fatigue strength of a lithium disilicate glass-ceramic. Methods Ninety bar-shaped specimens (1.0 × 1.0 × 12.0 mm) were prepared from Advanced Lithium...

IntroductionLow T cell receptor excision circles (TRECs) on newborn screen and severe T cell lymphopenia in a term newborn raise concern for severe combined immunodeficiency (SCID). Genetic polymorphisms in thiopurine me...

IntroductionAdenosine deaminase–deficient severe combined immunodeficiency (ADA-SCID) is an autosomal recessive disorder comprising ∼15% of SCID cases. Newborn screening (NBS) relies on T cell receptor excision circl...

Abstract Background Circulating cell-free DNA (cfDNA) is a promising biomarker for non-invasive early cancer detection. We integrated methylation entropy, a measure of DNA methylation heterogeneity, with other cfDNA feat...

The methods for loess collapsibility mainly include field immersion testing method and laboratory testing method. A majority of the results of laboratory testing method differ greatly from the engineering practice. The d...

Background: Axial spondyloarthritis (axSpA) can potentially progress to ankylosing spondylitis, and diagnostic delay may lead to irreversible structural damage. Although sacroiliac joint magnetic resonance imaging (MRI) ...

BackgroundCommon variable immunodeficiency (CVID) is diagnosed at ages ≥4 years with hypogammaglobulinemia across more than two immunoglobulin classes, leading to impaired vaccine responses, frequent infectious, autoim...

Pemanfaatan teknologi Internet of Things (IoT) dalam sektor pertanian semakin berkembang, terutama dalam upaya meningkatkan efisiensi dan ketepatan pengambilan keputusan berbasis data. Pertanian modern menuntut sistem mo...

Background Lynch syndrome (LS) is defined by having a pathogenic constitutional variant affecting one of the four mismatch repair (MMR) genes: MSH2, MLH1, MSH6 or PMS2. In 2017, National Institute for Health and Care Exc...

OBJETIVO: avaliar as atitudes e conhecimento dos obstetras das maternidades públicas da cidade de Salvador (MPS) sobre as recomendações do Ministério da Saúde para a profilaxia da transmissão vertical do vírus hum...

Formulation of the problem. In scientific research in sociology, education, physics, chemistry and other sciences, methods of correlation analysis are used. Correlation coefficients are used to determine the existence of...

Introduction Diabetes is increasingly prevalent in reproductive-aged women, but the association between social determinants of health (SDOH) and access to A1C monitoring after diagnosis are poorly understood. We explored...

Primary Immunodeficiencies (PI) include more than 550 monogenic disorders presenting with recurrent infections, autoimmunity, and significant morbidity. Early molecular diagnosis is essential for guiding targeted treatme...

In this paper, we propose an efficient diagnosis scheme to detect and locate the switching network defects/faults in reconfigurable array architecture. This diagnosis scheme performs the test of switching network based o...

The resolution of optimization problems is of great interest nowadays and has encouraged the development of various information technology methods to attempt solving them. There are several problems related to Software E...

The resolution of optimization problems is of great interest nowadays and has encouraged the development of various information technology methods to attempt solving them. There are several problems related to Software E...