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Abstract Background Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic inflammation and organ failure. Although its complex molecular...

Abstract Breast cancer is still the most significant contributor to morbidity and mortality among women in China. Despite advances in imaging and molecular testing, few reliable biomarkers exist for early detection and d...

Abstract Background Bacterial diseases include any illness caused by bacteria. Bacteria are tiny microorganisms that can only be seen with a microscope. Other types of microorganisms include viruses, fungi, and some para...

Abstract Background The role of extrachromosomal DNA (ecDNA)-related genes in osteosarcoma remains largely unexplored. The aim of this study is to investigate the association between ecDNA-related genes and prognosis and...

Abstract The increase in vehicle ownership and urban population puts a strain on roads and increases traffic congestion within developed and developing nations. Congestion affects an individual’s time and increases an ...

Abstract Lung cancer remains the leading cause of cancer incidence and mortality globally, yet its molecular mechanisms remain poorly understood. Recent studies highlight the role of protein lactylation in regulating tum...

Abstract Objective To explore new diagnostic markers and therapeutic targets associated with the histological types of thymoma. Methods The TCGA and GEO was used to gather genomic and clinical data from thymoma patients....

Di-Higgs production at the LHC associated with missing transverse energy is explored in the context of simplified models that generically parameterize a large class of models with heavy scalars and dark matter candidates...

Abstract This research employs hybrid machine learning techniques to optimize the mechanical properties of 3D-printed polylactic acid (PLA) lattice structures. By integrating random forest (RF) and XGBoost (XGB) algorith...

Abstract Failures of flexible pavements have been attributed to the indiscriminate use of lateritic soils without prior characterisation. This study investigates the compaction behaviour of lateritic soils at Ife-Sekona ...

Abstract Financial institutions continue to face a significant challenge with money laundering and need intelligent, scalable ways to detect illegal financial activity. This paper introduces a machine learning-driven pla...

Abstract Background Lung cancer remains the leading cause of cancer-related mortality worldwide. This study aimed to develop prognostic prediction models for lung squamous cell carcinoma (LUSC) through multi-omics integr...

Subjects / keywords: Python (Computer program language); Data structures (Computer science); Computer algorithms

We present an introduction to some of the state of the art in reduced order and surrogate modeling in gravitational-wave (GW) science. Approaches that we cover include principal component analysis, proper orthogonal (sin...