Search academic resources

ABSTRACT Background and Aims Nicotine dependence is a growing concern, particularly among young adults. While e‐cigarettes are marketed as smoking cessation tools, evidence suggests they may contribute to increased dep...

Abstract Background Cardiac fibrosis is a pivotal pathological process driving adverse cardiac remodeling and a defining feature of end-stage heart disease. Nicotine, a principal constituent of tobacco products, is now r...

Descriptive Consumer-Reported Outcome Measures (CROM) are self-reported survey outcome measures intended to measure observable characteristics and behaviors in research on tobacco- and nicotine-containing products (TNPs)...

Parkinson’s disease (PD) is characterized by profound metabolic disturbances in the brain, yet how these alterations vary across brain regions and respond to neuroprotective intervention remains poorly understood. Here...

The aim of the present study was to evaluate the possible involvement of GABAB receptors in the anxiolytic- and anxiogenic-like responses induced by nicotine in mice. Animals were exposed to nicotine only once. The acute...

AbstractPsychostimulants regulate behavioral responses in zebrafish via epigenetic mechanisms. We have previously shown that DNAmethylation and histone deacetylase (HDAC) inhibition abolish nicotine-induced conditioned p...

Given the well-documented pharmacological differences between nicotine and nornicotine enantiomers, understanding their distribution is essential. This knowledge also helps authenticate the enantiomers’ source (natural...

A previous study from our laboratory showed that baclofen (BAC, GABAB receptor agonist) was able to prevent the behavioral expression of nicotine (NIC) withdrawal syndrome. To further investigate the mechanisms underlyin...

ABSTRACT Nicotine, the most toxic factor in tobacco, can damage a wide range of biological molecules by inducing oxidative stress. This study aimed to investigate the protective effects of Teucrium polium Leaves extract ...

100 million adults and 15 million adolescents currently use e-cigarettes, a type of Electronic Nicotine Delivery System (ENDS) or Electronic Non-Nicotine Delivery System (ENNDS). While they were introduced as smoking ces...

Introduction: The first days of a quit attempt represent an important challenge to long-term abstinence, especially because of the changes that take place over this period. Objective: To examine whether smokers who have ...

A real-time electrochemical sensing strategy for nicotine monitoring in smoke streams was developed using additively manufactured three-dimensional (3D) based on conductive polymer composites. Disc-type microelectrodes (...

Background The high rate of long-term relapse is a major cause of smoking cessation failure. Recently, neurofeedback training has been widely used in the treatment of nicotine addiction; however, approximately 30% of sub...

BackgroundWith the highest cancer incidence and mortality rates in the country, rural Appalachia has experienced a decades-long health decline, due in part to high smoking rates. Cigarette smoking prevalence exceeds 30% ...

Subjects / keywords: Science

We examine and refine the Fagerström Tolerance Questionnaire (FTQ: Fagerström, 1978). The relation between each FTQ item and biochemical measures of heaviness of smoking was examined in 254 smokers. We found that the n...

Subjects / keywords: tobacco use, nicotine addiction, tobacco-related cancer, smoking cessation, addictive behaviour; Science

Nicotine use is more prevalent in patients with psychiatric disorders, especially those diagnosed with psychotic illnesses. Previously, this higher prevalence has been partially attributed to the potential ameliorative e...

Secondhand smoke (SHS) contains toxicants and carcinogens that are known to cause premature death and disease. Objectively measuring SHS exposure can support and evaluate smoke-free legislations. In Latin America, the mo...

Tobacco harm reduction (THR) using represents a pragmatic and realistic strategy, to which electronic nicotine delivery systems (ENDS) misperceptions act as a barrier. This paper explores ENDS misperceptions, especially ...

Abstract Objective: The aim of this study was to determine which individual characteristics of smokers are associated with their adherence to a support group for smoking cessation. Methods: Smokers from Porto Alegre, B...

Electronic cigarette (e-cigarette) use has risen rapidly over the past decade, particularly among adolescents and young adults, driven by perceptions of reduced harm compared with combustible cigarettes. Despite the abse...

Abstract Objective The current study presents the translation and adaptation of the 20-item Taiwan version of the Borderline Personality Inventory (BPI) into Brazilian Portuguese (BPI-P). Methods After translation an...

System change interventions, including staff training and policies for identification of smokers and provision of smoking cessation treatment and advice by clinicians or by specialists, had uncertain effects on abstinenc...