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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
Daniel F. Veber; Stephen R. Johnson; Hung‐Yuan Cheng; Brian R. Smith; Keith W. Ward; Kenneth D. Kopple · Journal of Medicinal Chemistry · 2002
Oral bioavailability measurements in rats for over 1100 drug candidates studied at SmithKline Beecham Pharmaceuticals (now GlaxoSmithKline) have allowed us to analyze the relative importance of molecular properties consi...
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