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The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
Article
Article
Damian Szklarczyk; John H. Morris; Helen Cook; Michael Kuhn; Stefan Wyder; Milan Simonovic; Alberto Santos; Nadezhda T. Doncheva · Nucleic Acids Research · 2016
A system-wide understanding of cellular function requires knowledge of all functional interactions between the expressed proteins. The STRING database aims to collect and integrate this information, by consolidating know...
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Analysis of protein-coding genetic variation in 60,706 humans
Article
Article
Monkol Lek; Konrad J. Karczewski; Eric Vallabh Minikel; Kaitlin E. Samocha; Eric Banks; Timothy R. Fennell; Anne O’Donnell‐Luria; James S. Ware · Nature · 2016
Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. Here we describe the aggregation and analysis of high-quality exome (protein-...
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