DNA Replication - Current Advances
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DNA Replication : Current Advances
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Book
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Material complementarioDNA Replication : Epigenetic Mechanisms and Gene Therapy Applications
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Book
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Material complementarioDNA Replication Controls
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Book
2 fuentes relacionadas
2 fuentes relacionadas
DOAB KBART
ISBN 9783038425694;9783038425687 · Book · Texto completo disponible
DOAB KBART
ISBN 9783038425731;9783038425724 · Book · Texto completo disponible
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Material complementarioDNA Replication Origins in Microbial Genomes
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Book
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Material complementarioDNA Replication Origins in Microbial Genomes, Volume 2
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Book
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Material complementarioDNA Replication Stress
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Book
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Material complementarioDNA Replication and Related Cellular Processes
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Book
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Material complementarioMaternal Low-Protein Diet Deregulates DNA Repair and DNA Replication Pathways in Female Offspring Mammary Gland Leading to Increased Chemically Induced Rat Carcinogenesis in Adulthood
Article
Article
Studies have shown that maternal malnutrition, especially a low-protein diet (LPD), plays a key role in the developmental mechanisms underlying mammary cancer programming in female offspring. However, the molecular pathw...
Idioma English
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Open AccessChapter Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication
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Chapter
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Open AccessFundamental Aspects of DNA Replication
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Book
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Material complementarioThe DNA Replication Machinery as Therapeutic Targets
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Book
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Material complementarioThe Mechanisms of DNA Replication
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Book
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Material complementarioMutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity
Article
Article
Translesion DNA polymerases (Pol) function in the bypass of template lesions to relieve stalled replication forks but also display potentially deleterious mutagenic phenotypes that contribute to antibiotic resistance in ...
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Open AccessIdentification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1
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Article
Replication Protein A (RPA) is a broadly conserved complex comprised of the RPA1, 2 and 3 subunits. RPA protects the exposed single-stranded DNA (ssDNA) during DNA replication and repair. Using structural modeling, we di...
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Open AccessMaintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants
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Material complementarioTranscription elongation can be sufficient, but is not necessary, to advance replication timing
Article
Article
Abstract DNA replication timing (RT) often correlates with transcription during cell fate transitions, yet notable exceptions indicate a complex relationship. Using a reductionist system in mouse embryonic stem cells, we...
LCC LCC:Biology (General)Idioma English
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Material complementarioLeukaemia Inhibitory Factor (LIF) induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK 1/2 activation
Article
Article
Leukemia inhibitory factor (LIF) and oncostatin M (OSM) induce DNA synthesis in Swiss 3T3 cells through common signaling mechanism(s), whereas other related cytokines such as interleukin-6 and ciliary neurotrophic factor...
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Open AccessA review on phytochemical and bacteriophage based therapeutic strategies for the management of Brucellosis
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Article
Brucellosis, a zoonotic disease, triggers severe inflammation and reproductive complications in both humans and animals. The standard treatment protocol relies on prolonged antibiotic courses, often combining streptomyci...
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Material complementarioAdenine Ribonucleotide (AXP) Depletion Due to Inherited Deficiency of Adenosine Deaminase 1 (ADA)
Article
Article
Adenosine deaminase 1-deficient severe combined immune deficiency (ADA-SCID) has widely been attributed to the toxic accumulation of adenine deoxyribonucleotides (dAXP) derived from 2’-deoxyadenosine (dAdo). The presen...
LCC LCC:Immunologic diseases. AllergyIdioma English
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Open AccessAnalysis of the Interaction Interfaces of the N-Terminal Domain from Pseudomonas aeruginosa MutL
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Article
Mismatch Repair System corrects mutations arising from DNA replication that escape from DNA polymerase proofreadingactivity. This system consists of three main proteins, MutS-L-H, responsible for lesion recognition and r...
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Open AccessBiological characteristics of intestinal organoids versus in vivo intestinal crypts and mechanisms underlying their differential responses to nobiletin
Thesis
Thesis
Abstract
Objective
Intestinal organoids serve as important tools for drug screening, but the extent to which they recapitulate in vivo tissue microenvironments and drug responses remains inadequately evaluated. This s...
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Open AccessCombined Immunodeficiency Manifests from S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
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Article
S-adenosylhomocysteine (SAH) hydrolase deficiency is a rare autosomal recessive disorder caused by pathogenic variants of the gene AHCY. Loss of SAH hydrolase causes SAH accumulation and impairs the methionine/S-adenosyl...
LCC LCC:Immunologic diseases. AllergyIdioma English
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Open AccessGut and skin microbiota of Bufo gargarizans tadpoles respond differently to temperature
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Article
Gut and skin microbiota impact host physiology and can be influenced by environmental changes, however, their reactions to rising environmental temperatures remain unclear. In this study, Bufo gargarizans tadpoles were e...
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Open Access