Search academic resources

Abstract Introduction Compared to other types of caregiver, spouse-caregivers tend to be closer to people with Alzheimer’s disease (PwAD) because of their different position in the relationship. We designed this stud...

Context: Signal transducer and activator of transcription 5b (STAT5b) deficiency, first reported in a patient who carried a p.Ala630Pro missense mutation in the Src homology 2 (SH2) domain, results in a rare clinical con...

Events at a receptor ectodomain affect the intracellular domain conformation, activating signal transduction (out-to-in conformational effects). We investigated there verse direction (in-to-out) where the intracellular d...

UDP-glucose:glycoprotein glucosyltransferase (UGGT) flags misfolded glycoproteins for ER retention. We report crystal structures of full-length Chaetomium thermophilum UGGT (CtUGGT), two CtUGGT double-cysteine mutants, a...

Tripartite motif (TRIM)7 is an E3 ubiquitin ligase that was first identified through its interaction with glycogenin-1 (GN1), the autoglucosyltransferase that initiates glycogen biosynthesis. A growing body of evidence i...

Abstract In machinery fault diagnosis, labeled data are always difficult or even impossible to obtain. Transfer learning can leverage related fault diagnosis knowledge from fully labeled source domain to enhance the faul...

Background: Despite growing environmental awareness, significant gaps persist between environmentally sustainable consumption intentions and behaviors. Most research examines barriers to environmentally sustainable consu...

Question-answering (QA) has been a crucial NLP (Natural Language Processing) task for a long time. As an umbrella term, QA has multiple sub-tasks under its hood. Question classification (QC) is one of the most important ...

Ontologies can be used in Domain Oriented Software Engineering Environments (DOSEEs) to organize and describe knowledge and to support management, acquisition and sharing of knowledge regarding some domain. However, onto...

Reuse-oriented software methodologies have emerged to provide a set of rules or guides for development and evolution of software systems by reusing existing domain engineering artefacts such as requirements, architecture...

Reuse-oriented software methodologies have emerged to provide a set of rules or guides for development and evolution of software systems by reusing existing domain engineering artefacts such as requirements, architecture...

Work-related extended availability (WREA) describes a state of being available for work matters while physically being in a different life domain. There is ample evidence for the negative effects of WREA, but moderator e...

This study pioneered the construction or adaptation of a Spanish version of the Teacher as Social Context (TASC) Questionnaire. The current study included a sample of 410 secondary education teachers in Spain. A confirma...

Abstract Epilepsy is a chronic neurological disease that profoundly impacts patients’ daily lives. Electroencephalography (EEG) serves as a crucial tool for the clinical diagnosis of epilepsy and other brain disorders....

Cruzipain (Cz), the major cysteine proteinase of Trypanosoma cruzi, is a glycoprotein that contains sulfated high-mannose-type oligosaccharides. We have previously determined that these sulfate groups are targets of sp...

El basamento del sur de la Cuenca Neuquina está integrado por metamorfitas paleozoicas de alto grado metamórfico. En el presente trabajo la fábrica tectónica de estas rocas fue analizada a través de estudios de camp...

Immunophilins are a family of proteins whose signature domain is the peptidylprolylisomerase domain. High molecular weight immunophilins are characterized by the additional presence of tetratricopeptide-repeats (TPR) thr...

The Bruton nonreceptor protein-tyrosine kinase (BTK) plays a central role in B cell antigen receptor signaling. Following B cell receptor activation, the Src protein kinase Lyn and the spleen protein kinase (Syk) activat...

The efferent pathway mediated by the medial olivocochlear (MOC) system regulates the excitability of outer hair cells (OHC). In re- sponse to sound overstimulation, the MOC system activates nico- tinic acetylcholine rece...

Purpose – This study aimed to develop and evaluate CircuitPintar, a website-based learning medium designed to improve the competencies of vocational high school students in the Basic Electrical Theory element of the El...

ABSTRACT Adolescence is a vulnerable period for the onset of mental disorders and risk behaviours. Whole‐school interventions hold vast potential in improving mental health and preventing risk behaviours in this develo...

Sensing the scattered fields of single metallic nanostructures is a crucial step towards the applications of isolated plasmonic antennas, such as for the sensing of single molecules or nanoparticles. In the past, both ne...

Abstract Background Studies of health-related quality of life among workers have generated varying results. The purpose of this study was to conduct a systematic review to synthesize the scores of health-related quality ...

This paper discusses the nature of the metaphorical transfer from the source domain to the target domain. More specifically, it explores the question as to how the mapping links between features of the source and the tar...