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How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?
Article
Article
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?
Di Ianni, Mauricio Emiliano et al · Smart Science & Technology · 2014 · ISSN 2330-3883
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of ex...
Idioma Spanish
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Neglected Diseases: Drug Development for Chagas Disease as an Example
Book
Book
Neglected Diseases: Drug Development for Chagas Disease as an Example
Garcia Bournissen, Facundo et al · Springer Nature Switzerland AG · 2015
Neglected diseases (NDs), also known as neglected tropical diseases, are a group of chronic diseases that disproportionately affect the poorest populations in the world. Largely ignored, children comprise a significant p...
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Drugs and Development: Exploring Nuances Based on the Accounts of Nigerian Retail Dealers
Article
Article
Drugs and Development: Exploring Nuances Based on the Accounts of Nigerian Retail Dealers
Ediomo-Ubong Ekpo Nelson · LSE Press · 2024 · ISSN 2516-7227
The production, distribution, and consumption of drugs has long been seen as a threat to social and economic development. On the other hand, conditions of unemployment and poverty foster expansion of illegal drug markets...
LCC LCC:Social pathology. Social and public welfare. Criminology; TENDOlNvY2lhbCBoaXN0b3J5IGFuZCBjb25kaXRpb25zLiBTb2NpYWwgcHIdioma English
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Design and Development of Drug Formulation Classification Information System
Article
Article
Design and Development of Drug Formulation Classification Information System
Retno Agus Setiawan et al · Lembaga Penelitian dan Pengabdian kepada Masyarakat · 2024 · ISSN 0216-9495
The increasing complexity of pharmaceutical management in pharmacies demands efficient systems to streamline drug classification and inventory control. As pharmacies handle a diverse range of formulations, including tabl...
LCC TENDOlRlY2hub2xvZ3k~Idioma English
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Hydrogel-based solid dispersion: development of sustained release drug delivery for aceclofenac indicated for the relief of pain and inflammation
Article
Article
Hydrogel-based solid dispersion: development of sustained release drug delivery for aceclofenac indicated for the relief of pain and inflammation
Sana Shahzad et al · AMMANIF · 2025 · ISSN 2521-0521
Developing aceclofenac hydrogel-based solid dispersions enclosed in two modified gelatin capsules for long-term medication delivery was the aim of this study. Eudragit L 100 and hydroxypropyl methylcellulose acetate succ...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma English
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Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone
Article
Article
Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone
Namra Chaudhary et al · AMMANIF · 2023 · ISSN 2521-0521
Aim and Objective: The study aimed to manufacture Bucco-adhesive tablets of Risperidone and characterize the effectiveness of the drug by incorporating it into the mucoadhesive drug delivery system. The sustained release...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma English
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Hybrid nanogel systems' recent development: manufacturing and applications in drug simultaneous delivery associated imaging approach
Article
Article
Hybrid nanogel systems' recent development: manufacturing and applications in drug simultaneous delivery associated imaging approach
Humaira Sultana et al · AMMANIF · 2023 · ISSN 2521-0521
Researchers in pharmacy are paying increasingly close attention to nanogel-based multifunctional drug delivery systems, particularly hybrid nanogels and multicompartment nanogels because they can lead to the achievement ...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma English
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Development and evaluation of modified locust bean microparticles for controlled drug delivery
Article
Article
Development and evaluation of modified locust bean microparticles for controlled drug delivery
Gowda, D. Vishakant et al · SEDICI UNLP · 2011
The objective of the present study was to minimize the unwanted toxic effects of antihypertensive drug diltiazem hydrochloride (DTZ) by kinetic control of drug release from microparticles using chemically modified locust...
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Formulation development and evaluation of thermosensitive gel for vaginal drug delivery
Article
Article
Formulation development and evaluation of thermosensitive gel for vaginal drug delivery
Bhat, Sudeendra R. et al · SEDICI UNLP · 2010
A new reversible thermosensitive drug delivery system was designed and prepared by using chitosan and glycerophosphate with or without poly (ethylene glycol) and used as an a carrier for the Miconazole nitrate, an antifu...
Idioma Spanish
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In vitro and In vivo toxicology evaluation to determine suitable biomedical Polymers for development of a papain-containing drug delivery system
Article
Article
In vitro and In vivo toxicology evaluation to determine suitable biomedical Polymers for development of a papain-containing drug delivery system
Alcântara, Mara T. S. et al · SEDICI UNLP · 2011
Papain has been known by many decades for wounded tissues repair. However, papain stability is not high enough to be commercialized in a stable pharmaceutical form; therefore its use is limited. The strategy to entrap pa...
Idioma English
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Nano based drug delivery systems: recent developments and future prospects
Text / resource
Text / resource
Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra; Gitishree Das; Leonardo Fernandes Fraceto; Estefânia Vangelie Ramos Campos; María del Pilar Rodríguez-Torres; Laura Susana Acosta‐Torres; L.A. Dı́az-Torres; Renato Grillo · Journal of Nanobiotechnology · 2018
Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to spe...
Idioma English
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
Text / resource
Text / resource
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
Christopher A. Lipinski; Franco Lombardo; Beryl W. Dominy; Paul J. Feeney · Advanced Drug Delivery Reviews · 2001
Subjects / keywords: Solubility; Drug discovery; Thermodynamics; Chemistry; Permeability (electromagnetism); Computational chemistry; Physics; Organic chemistry; Membrane; Biochemistry
Idioma English
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Design and development of gastro retentive drug delivery System of tramadol hydrochloride
Article
Article
Design and development of gastro retentive drug delivery System of tramadol hydrochloride
Rathore, Devashish et al · SEDICI UNLP · 2011
The present investigation concerns the development of floating tablets of tramadol hydrochloride, which after oral administration are designed to prolong the gastric residence time; improves the drug bioavailability, red...
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Design, development and in vitro evaluation of swelling gastro retentive drug delivery system for type 2 diabetic patients
Article
Article
Design, development and in vitro evaluation of swelling gastro retentive drug delivery system for type 2 diabetic patients
Ige, Pradum P. et al · SEDICI UNLP · 2011
The aim of the present study was to develop sustained release swelling tablets containing metformin HCl and confine them into the stomach for enhancement of bioavailability. The different batches were manufactured by wet...
Idioma English
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Drug Design, Development and Therapy
Article
Article
Drug Design, Development and Therapy
Dove Medical Press; United Kingdom · ISSN 1177-8881
Subjects / keywords: drug design, drug safety, drug development, pharmaecuticals; Medicine: Therapeutics. Pharmacology
Idioma English
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Tapa de An epic history of pharmacy: pharmacy in the Ancient World
E-book
An epic history of pharmacy: pharmacy in the Ancient World
Nogales, Luis Marcos · Ediciones Universidad de Salamanca · 2018 · ISBN 9788490128237
What really sets humankind apart from other species is our fondness of drugs. This vale of tears, full of plants and animals to tame, was the breeding ground for cultures and civilizations with a penchant for developing ...
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A potential impact of artificial intelligence on pharmaceutical drug design and clinical trials
Article
Article
A potential impact of artificial intelligence on pharmaceutical drug design and clinical trials
Muhammad Naeem Aamir et al · AMMANIF · 2025 · ISSN 2521-0521
Pharmaceutical technology has increasingly integrated artificial intelligence (AI) in recent years. This technology offers significant benefits, including saving time and money while enhancing the understanding of the re...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma English
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From biosimilars to breakthroughs: regulatory convergence toward evidence-efficient development of monoclonal antibodies
Article
Article
From biosimilars to breakthroughs: regulatory convergence toward evidence-efficient development of monoclonal antibodies
Sarfaraz K. Niazi · Frontiers Media S.A · 2026 · ISSN 2674-0338
Regulatory science governing monoclonal antibody development has undergone a profound transformation over the past decade, shifting from empiricism-driven paradigms toward evidence-efficient, mechanism-based frameworks g...
LCC LCC:Therapeutics. PharmacologyIdioma English
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Plasma proteome-wide Mendelian randomization reveals multi-ancestry drug targets for gastric cancer
Article
Article
Plasma proteome-wide Mendelian randomization reveals multi-ancestry drug targets for gastric cancer
Peng Zhi et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundGastric cancer (GC) exhibits marked epidemiological differences between European (EUR) and East Asian (EAS) populations, with significantly higher incidence rates in EAS. Circulating proteins represent promisin...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma English
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Quantum Computing and Quantum Technologies in Drug Discovery and Therapeutics: Evidence, Benchmarking, and Translational Integration
Article
Article
Quantum Computing and Quantum Technologies in Drug Discovery and Therapeutics: Evidence, Benchmarking, and Translational Integration
Niazi SK · Dove Medical Press · 2026 · ISSN 1177-8881
Sarfaraz K Niazi Department of Pharmaceutical Sciences, University of Illinois, Chicago, IL, 60612, USACorrespondence: Sarfaraz K Niazi, Email sniazi3@uic.eduAbstract: Quantum technologies—quantum computing, quantum se...
LCC LCC:Therapeutics. PharmacologyIdioma English
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Tools of the trade: leveraging 3D in vitro models to advance silicosis research
Article
Article
Tools of the trade: leveraging 3D in vitro models to advance silicosis research
Ellen Donohoe et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
Silicosis is an occupational fibrotic lung disease representing a major public health crisis, and places a significant burden on patients and healthcare systems. There are no curative treatments for patients with silicos...
LCC LCC:Therapeutics. PharmacologyIdioma English
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Constructing Neuroinflammation‐On‐A‐Chip for Traditional Chinese Medicine Extracts Evaluation
Article
Article
Constructing Neuroinflammation‐On‐A‐Chip for Traditional Chinese Medicine Extracts Evaluation
Xirui Wang et al · Wiley-VCH · 2026 · ISSN 2751-1871
ABSTRACT Neuroinflammation is a core pathological mechanism in neurodegenerative diseases. Although natural many compounds, derived from traditional Chinese medicine have shown promise in modulating neuroinflammation, co...
LCC TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma English
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Equity and representation in oncology clinical evidence for FDA-approved treatments and the impact of COVID-19
Article
Article
Equity and representation in oncology clinical evidence for FDA-approved treatments and the impact of COVID-19
Hao Cheng et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundPivotal clinical trials form the evidentiary foundation for FDA oncology drug approvals, yet persistent disparities in participant demographics may limit the generalizability and equity of cancer care. This stu...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma English
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SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Article
Article
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina; Olivier Michielin; Vincent Zoete · Scientific Reports · 2017
To be effective as a drug, a potent molecule must reach its target in the body in sufficient concentration, and stay there in a bioactive form long enough for the expected biologic events to occur. Drug development invol...
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