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Subjects / keywords: Medicine: Medicine (General); Science: Biology (General): Genetics

Subjects / keywords: biochemistry, cell biology, molecular genetics, structural biology, protein deficiencies, hereditary pathogenesis; Medicine: Medicine (General); Science: Biology (General): Genetics

Abstract A key factor contributing to the success of Darwin and Wallace’s theory of biological evolution by natural selection was its population-level perspective. This conceptual framework was not immediately adopted,...

La utilidad de los depósitos de material genético humano para la investigación médica, antropológica y básica es indiscutible. Los repositorios y bancos permiten compartir las muestras entre distintos laboratorios ...

There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix ...

BackgroundThe research on human microbiota-associated (HMA) animal models is an important tool for studying the human microbiome and holds great potential for elucidating disease mechanisms and microbe-based therapeutic ...

Together with the environment, genetic factors can significantly influence sleep and its architecture. Monozygotic twins have greater similarity in terms of latency and duration of sleep cycles than dizygotic twins, in a...

The coevolution of the human diet and gut microbiome has played a pivotal role in shaping metabolic, immune, and epigenetic functions across human history. Dietary transitions from high-fiber ancestral patterns to modern...

Through the study of human genetic diversity, it can be predicted that complex traits, such as height and obesity, will be demonstrated. With the development of a new design technique using Surface Plasmon Resonance (SPR...

Livestock genomics is aimed at dissecting the genetic control of variation in economically important trait, such as disease resistance and product yield/quality. Unraveling the genetic control of such complex traits rema...

Deficiency of adenosine deaminase 2 (DADA2) was identified in 2014 as a novel inborn error of immunity caused by biallelic pathogenic variants in ADA2. DADA2 patients express two predominant clinical phenotypes: (1) auto...

Gut microbial communities represent one source of human genetic and metabolic diversity. To examine how gut microbiomes differ among human populations, here we characterize bacterial species in fecal samples from 531 ind...

Fil: Casanueva, Mario. Universidad Autónoma Metropolitana. Unidad Cuajimalpa. Departamento de Humanidades; México. Fil: Méndez, Diego. Universidad Autónoma Metropolitana. Unidad Cuajimalpa. Departamento de Humanidade...

The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report comp...

This review collates and examines critically a theoretically convergent but widely dispersed body of research on the influence of external environments on the functioning of families as contexts of human development. Inv...

Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although di...

In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip system with the objective of improving upon currently used measures of gene expression. Our analyses ma...

Subjects / keywords: Human genetics; Smoking; Social pathology; Pesticide residues in food