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Neste estudo, comprimidos matriciais de captopril foram desenvolvidos utilizando-se hidroxipropilmetilcelulose (HPMC) e quitosana (QTS) em diferentes proporções (50:50, 60:40, 40:60, 20:80), por compressão direta. Os ...

High-performance liquid chromatography (HPLC) and UV–vis spectrophotometry are indispensable techniques in pharmaceutical and food analysis, yet students often struggle to connect theoretical principles with real-world...

Se estudiaron las propiedades de las tabletas de metronidazol/ Carbopol971P NF de liberación sostenida, variando la proporción del lubricante, con y sin bicarbonato de sodio. Las variables estudiadas incluyen la dureza...

The purpose of this paper was to produce controlled-release matrices with 120 mg of propranolol hydrochloride (PHCl) employing hydroxypropyl methylcellulose (HPMC, Methocel® K100) as the gel forming barrier. Although th...

The present study was undertaken to evaluate the effect of glyceryl monostearate (GMS) and stearic acid (SA) on the release profile of gliclazide from the matrix. Matrix tablets for the controlled delivery of gliclazide ...

Hydrophilic matrix tablets were developed with acyclovir (ACV), using hypromelose and polyethylene oxide (PEO) in different concentrations. Matrix tablets obtained in each formulation were evaluated to determine the weig...

The purpose of the present study was to evaluate the effect of pure and blended mixtures, with different compositions of hydroxy propyl methyl cellulose (HPMC) and carnauba wax (CW) on the release of diclofenac potassium...

A novel polymer, chemically modified chitosan was synthesized by reacting with hydrochloride salt of 2-aminoethanoyl chloride. Formation of novel chemically modified chitosan was confirmed by FTIR and NMR spectroscopy an...

Se evaluó el comportamiento de diferentes polímeros de derivados celulósicos y vinílicos utili- zados en la elaboración de comprimidos de ácido acetilsalicílico (AAS) formulados como matríz hidrofilica. Se realiz...