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Microarray analysis workflow based on a genetic algorithm to discover potential hub genes
Article
Article
Microarray analysis workflow based on a genetic algorithm to discover potential hub genes
Carballido, Jessica Andrea · Bentham Science Publishers · 2022 · ISSN 1574-8936
This paper presents a sequence of steps oriented to gain biological knowledge from microar-ray gene expression data. The pipeline's core is a canonical multi-objective Genetic Algorithm (GA), which takes a gene expressio...
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Microarray molecular mapping of horses with severe asthma
Article
Article
Microarray molecular mapping of horses with severe asthma
Samuel J. White et al · Oxford University Press · 2024 · ISSN 0891-6640
Abstract Background Severe asthma (SA) in horses, resembling human asthma, is a prevalent, debilitating allergic respiratory condition marked by elevated allergen‐specific immunoglobulin E (IgE) against environmental p...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma English
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Micro y nanotecnología en medicina: los chips o microarrays de ADN. Encuentros multidisciplinares, 4 (12)
Article
Article
Micro y nanotecnología en medicina: los chips o microarrays de ADN. Encuentros multidisciplinares, 4 (12)
Dopazo González, Ana · D - Fundación General de la Universidad Autónoma de Madrid · 2009 · ISSN 1139-9325
Subjects / keywords: Ciencias Sociales; General
Idioma Spanish
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Application of chromosomal microarray analysis for fetuses with nasal bone agenesis or hypoplasia
Article
Article
Application of chromosomal microarray analysis for fetuses with nasal bone agenesis or hypoplasia
Keqin Jin et al · BMC · 2026 · ISSN 1755-8166
Abstract Objective To explore the utility of microarray technology in prenatal diagnosis of nasal bone agenesis or hypoplasia. Methods Between July 2018 to October 2023, several cases of abnormal nasal bone development w...
LCC LCC:GeneticsIdioma English
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Development of a comprehensive protein microarray for immunoglobulin E profiling in horses with severe asthma
Article
Article
Development of a comprehensive protein microarray for immunoglobulin E profiling in horses with severe asthma
Samuel White et al · Oxford University Press · 2019 · ISSN 0891-6640
Abstract Background Severe asthma in horses, known as severe equine asthma (SEA), is a prevalent, performance‐limiting disease associated with increased allergen‐specific immunoglobulin E (IgE) against a range of env...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma English
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Estudos de expressão gênica utilizando-se microarrays: delineamento, análise, e aplicações na pesquisa zootécnica Microarray gene expression studies: experimental design, statistical data analysis, and applications in livestock research
Article
Article
Estudos de expressão gênica utilizando-se microarrays: delineamento, análise, e aplicações na pesquisa zootécnica Microarray gene expression studies: experimental design, statistical data analysis, and applications in livestock research
Guilherme Jordão de Magalhães Rosa et al · Sociedade Brasileira de Zootecnia · 2007 · ISSN 1516-3598
A tecnologia de microarrays, ou microarranjos de DNA, possibilita a avaliação simultânea da expressão de milhares de genes em diferentes tecidos em determinado organismo, em diferentes estágios de desenvolvimento ou...
LCC LCC:Animal cultureIdioma English
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Genetic diagnosis in fetal hydronephrosis: assessment using chromosomal microarray analysis and whole-genome sequencing
Article
Article
Genetic diagnosis in fetal hydronephrosis: assessment using chromosomal microarray analysis and whole-genome sequencing
Jing Wang et al · BMC · 2026 · ISSN 1479-7364
Abstract Background Antenatal hydronephrosis (AHN) is a common urological abnormality identified during prenatal ultrasound examination, with heterogeneous underlying causes. This study aimed to investigate the genetic e...
LCC LCC:Medicine; LCC:GeneticsIdioma English
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Glutathione peroxidase 2 expression in human tumors: a tissue microarray study on 18,555 tumors
Article
Article
Glutathione peroxidase 2 expression in human tumors: a tissue microarray study on 18,555 tumors
Viktoria Chirico et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundGlutathione peroxidase 2 (GPX2) has a pivotal role in removing reactive oxygen species (ROS) from cells. Although the number of studies analyzing GPX2 in cancer is still limited, data suggesting a role of alter...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma English
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Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction
Article
Article
Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction
Wendorff, Mareike et al · Frontiers Media · 2020 · ISSN 1664-3224
Human Leukocyte Antigen class II (HLA-II) molecules present peptides to T lymphocytes and play an important role in adaptive immune responses. Characterizing the binding specificity of single HLA-II molecules has profoun...
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Dizygotic twin pseudochimaerism initially diagnosed as mosaic Klinefelter syndrome on microarray: case report
Article
Article
Dizygotic twin pseudochimaerism initially diagnosed as mosaic Klinefelter syndrome on microarray: case report
Declan O’Rourke et al · BMJ Publishing Group · 2025 · ISSN 3050-2551
Background Chimaerism is a rare genetic condition where an individual possesses two or more distinct cell lines originating from different zygotes. This case report highlights the diagnostic challenge presented by pseudo...
LCC LCC:GeneticsIdioma English
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Protein microarray allergen profiling in bronchoalveolar lavage fluid and serum of horses with asthma
Article
Article
Protein microarray allergen profiling in bronchoalveolar lavage fluid and serum of horses with asthma
Michelle Wyler et al · Oxford University Press · 2023 · ISSN 0891-6640
Abstract Background The diagnostic value of allergen‐specific immunoglobulin E (IgE) in horses with asthma is uncertain. A recently developed protein microarray detected abnormally high latex‐specific IgE concentrati...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma English
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XIAP Deficiency Caused by a Deletion in the Noncoding Exon 1 Identified by Chromosomal Microarray
Article
Article
XIAP Deficiency Caused by a Deletion in the Noncoding Exon 1 Identified by Chromosomal Microarray
Sean Duke et al · Rockefeller University Press · 2026 · ISSN 3065-8993
X-linked inhibitor of apoptosis (XIAP) is essential for innate and adaptive immune responses, including programmed cell death inhibition, NFkB and MAPK activation, NLRP3 inflammasome activity regulation, and TNFR signali...
LCC LCC:Immunologic diseases. AllergyIdioma English
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Aberrant expression of BDNF might serve as a candidate target for cocaine-induced psychosis: insights from bioinformatics analysis and microarray validation
Article
Article
Aberrant expression of BDNF might serve as a candidate target for cocaine-induced psychosis: insights from bioinformatics analysis and microarray validation
Jiang Du et al · Wiley · 2021 · ISSN 2517-729X
LCC TENDOlBzeWNoaWF0cnk~Idioma English
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Automatic Spot Adressing in cDNA Microarray Images
Article
Article
Automatic Spot Adressing in cDNA Microarray Images
Larese, Mónica G. et al · SEDICI UNLP · 2008
Complementary DNA (cDNA) microarrays are a powerful high throughput technology developed in the last decade allowing researchers to analyze the behaviour and interaction of thousands of genes simultaneously. The large am...
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GSVA: gene set variation analysis for microarray and RNA-Seq data
Article
Article
GSVA: gene set variation analysis for microarray and RNA-Seq data
Sonja Hänzelmann; Robert Castelo; Justin Guinney · BMC Bioinformatics · 2013
BACKGROUND: Gene set enrichment (GSE) analysis is a popular framework for condensing information from gene expression profiles into a pathway or signature summary. The strengths of this approach over single gene analysis...
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Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
Article
Article
Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
Mark Schena; Dari Shalon; Ronald W. Davis; Patrick O. Brown · Science · 1995
A high-capacity system was developed to monitor the expression of many genes in parallel. Microarrays prepared by high-speed robotic printing of complementary DNAs on glass were used for quantitative expression measureme...
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Significance analysis of microarrays applied to the ionizing radiation response
Article
Article
Significance analysis of microarrays applied to the ionizing radiation response
Virginia Goss Tusher; Robert Tibshirani; Gilbert Chu · Proceedings of the National Academy of Sciences · 2001
Microarrays can measure the expression of thousands of genes to identify changes in expression between different biological states. Methods are needed to determine the significance of these changes while accounting for t...
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limma powers differential expression analyses for RNA-sequencing and microarray studies
Article
Article
limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie; Belinda Phipson; Di Wu; Yifang Hu; Charity W. Law; Wei Shi; Gordon K. Smyth · Nucleic Acids Research · 2015
limma is an R/Bioconductor software package that provides an integrated solution for analysing data from gene expression experiments. It contains rich features for handling complex experimental designs and for informatio...
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Adjusting batch effects in microarray expression data using empirical Bayes methods
Article
Article
Adjusting batch effects in microarray expression data using empirical Bayes methods
W. Evan Johnson; Cheng Li; Ariel Rabinovic · Biostatistics · 2006
Non-biological experimental variation or "batch effects" are commonly observed across multiple batches of microarray experiments, often rendering the task of combining data from these batches difficult. The ability to co...
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Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
Article
Article
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004
The problem of identifying differentially expressed genes in designed microarray experiments is considered. Lonnstedt and Speed (2002) derived an expression for the posterior odds of differential expression in a replicat...
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Papel de los receptores de estrógenos alfa en el crecimiento de carcinomas mamarios murinos con respuesta diferencial a progestágenos
E-book
E-book
Papel de los receptores de estrógenos alfa en el crecimiento de carcinomas mamarios murinos con respuesta diferencial a progestágenos
Giulianelli, Sebastián Jesús · B - Universidad de Buenos Aires · 2009
Los mecanismos por los cuales los estrógenos y los progestágenos, a través de sus respectivos receptores (RE y RP), participan en el desarrollo y crecimiento del cáncer de mama es un tema controversial y de gran inte...
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Crx broadly modulates the pineal transcriptome
Article
Article
Crx broadly modulates the pineal transcriptome
Rovsing, Louise et al · Wiley Blackwell Publishing, Inc · 2011 · ISSN 0022-3042
Cone-rod homeobox (Crx) encodes Crx, a transcription factor expressed selectively in retinal photoreceptors and pinealocytes, the major cell type of the pineal gland. In this study, the influence of Crx on the mammalian ...
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Delineamento de experimentos em genética genômica Experimental design in genetical genomics
Article
Article
Delineamento de experimentos em genética genômica Experimental design in genetical genomics
Guilherme Jordão de Magalhães Rosa · Sociedade Brasileira de Zootecnia · 2007 · ISSN 1516-3598
Genética genômica é um termo utilizado para representar o estudo de processos genéticos controladores de caracteres fenotípicos de herança complexa, a partir da análise conjunta de informação relativa a fenótip...
LCC LCC:Animal cultureIdioma English
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Effects of BST and high energy diet on gene expression in mammary parenchyma of dairy heifers
Article
Article
Effects of BST and high energy diet on gene expression in mammary parenchyma of dairy heifers
Betina Joyce Lew et al · Sociedade Brasileira de Zootecnia · 2013 · ISSN 1806-9290
The objective of this study was to determine the effects of dietary energy and recombinant bovine somatotropin (bST) injection to identify genes that might control mammogenesis. Total RNA was extracted from the parenchym...
LCC LCC:Animal cultureIdioma English
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