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112 results found.

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Proteomics analysis revealed the mechanism of differential egg productive in geese
Article
Article
Lei Yang et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2026 · ISSN 1678-4162
ABSTRACT The Western Anhui white goose is a highly esteemed breed in our country, renowned for its superior meat quality and exceptional egg-laying performance. As the primary reproductive organ in poultry, the ovary sig...
LCC LCC:Animal cultureIdioma English
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Open Access
Chemical proteomics reveals sinomenine’s anti-inflammatory mechanism through serum protein covalent modification
Article
Article
Meixian Liu et al · BMC · 2026 · ISSN 1749-8546
Abstract Background Covalent protein modification by drugs or their reactive metabolites has emerged as an important mechanism underlying pharmacological activity. However, its contribution to the therapeutic effects of ...
LCC TENDOk90aGVyIHN5c3RlbXMgb2YgbWVkaWNpbmU~Idioma English
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Complementary Muscle Metabolomics and Proteomics of Muscle in Cows With Post‐Calving Ketosis
Article
Article
Tao Tang et al · Oxford University Press · 2025 · ISSN 0891-6640
ABSTRACT Background The muscle tissue of dairy cows is a site of β‐hydroxybutyrate (BHBA) metabolism. The mechanisms underlying the changes in proteins and metabolites in the muscle tissue of cows with ketosis remain ...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma English
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Comprehensive Overview of Bottom-Up Proteomics Using Mass Spectrometry
Article
Article
Jiang, Yuming et al · American Chemical Society · 2024 · ISSN 2694-250X
Proteomics is the large scale study of protein structure and function from biological systems through protein identification and quantification. “Shotgun proteomics” or “bottom-up proteomics” is the prevailing st...
Idioma English
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In silico comparative proteomics and structural analysis of Theileria species reveals conserved druggable targets for anti-theilerial therapy
Article
Article
Hizbullah Khan et al · BMC · 2026 · ISSN 1471-2180
Abstract Theileriosis, a tick-borne disease caused by apicomplexan parasites of the genus Theileria, poses a major constraint to livestock productivity worldwide. Existing chemotherapeutics are increasingly limited by ho...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma English
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Isobaric quantitative proteomics reveals altered extracellular matrix, cytoskeletal, and degradation pathways in glaucomatous trabecular meshwork cells
Article
Article
Paul Holden et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Glaucoma trabecular meshwork (GTM) cells cultured in vitro retain many characteristics of their in situ phenotype. Here, we used isobaric tandem mass tags (TMTpro) to label peptides from glaucomatous and non-gla...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma English
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DSCAML1+ extracellular vesicles revealed by single-vesicle proteomics as a novel biomarker and therapeutic target in myocardial infarction
Article
Article
Nan Liu et al · BMC · 2026 · ISSN 1477-3155
Abstract The early and accurate diagnosis of acute myocardial infarction (AMI) remains a significant clinical challenge. To this end, we profiled the surface proteome of individual plasma extracellular vesicles (EVs) fro...
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Morphology, histology, and proteomics of the testicle and epididymis of European quail fed calcium anacardate
Article
Article
Rafael de Sousa Ferreira et al · Sociedade Brasileira de Zootecnia · 2023 · ISSN 1806-9290
ABSTRACT This report examines the effects of calcium anacardate (CA) on the morphology, histology, and proteomics of the testes and epididymal ducts of breeding quail. To that end, 22 140-day-old males were grouped in fo...
LCC LCC:Animal cultureIdioma English
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Integrated transcriptomics, proteomics, and metabolomics analyses reveal key regulatory pathways related to the development of viral symptoms in tomato plants
Article
Article
Kaijie Shang et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Viral infections of tomato plants present a significant threat to tomato production and yield. Mixed viral infections are common in field-grown tomatoes and are known to exacerbate disease symptoms; h...
LCC TENDOkJvdGFueQ~~Idioma English
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Open Access
Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics
Article
Article
Shao‐En Ong; Blagoy Blagoev; Irina Kratchmarova; Dan Bach Kristensen; Hanno Steen; Akhilesh Pandey; Matthias Mann · Molecular & Cellular Proteomics · 2002
Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous...
Idioma English
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ExPASy: the proteomics server for in-depth protein knowledge and analysis
Article
Article
Elisabeth Gasteiger · Nucleic Acids Research · 2003
The ExPASy (the Expert Protein Analysis System) World Wide Web server (http://www.expasy.org), is provided as a service to the life science community by a multidisciplinary team at the Swiss Institute of Bioinformatics (...
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The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
Article
Article
Yasset Pérez‐Riverol; Jingwen Bai; Chakradhar Bandla; David García‐Seisdedos; Suresh Hewapathirana; Selvakumar Kamatchinathan; Deepti J Kundu; Ananth Prakash · Nucleic Acids Research · 2021
The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is one of the founding members of the global Proteom...
Idioma English
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Clinical Proteomics
Article
Article
BMC; United Kingdom · ISSN 1559-0275
Subjects / keywords: translational proteomics, molecular medicine; Medicine
Idioma English
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Open Access
Genomics, Proteomics & Bioinformatics
Article
Article
Oxford University Press; United Kingdom · ISSN 1672-0229
Subjects / keywords: genomics, proteomics, bioinformatics, epigenomics; Science: Biology (General); Medicine: Medicine (General): Computer applications to medicine. Medical informatics
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Molecular & Cellular Proteomics
Article
Article
Elsevier; United States · ISSN 1535-9476
Subjects / keywords: biochemistry, molecular biology, proteomics, protein science, systems biology, bioinformatics; Science: Chemistry: Organic chemistry: Biochemistry
Idioma English
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Open Access
APOE4 Exerts Partial Diet-dependent Effects on Energy Expenditure and Skeletal Muscle Mitochondrial Pathways in a Preclinical Model
Article
Article
Chelsea N Johnson et al · American Physiological Society · 2025 · ISSN 2633-8823
Abstract Apolipoprotein E4 (APOE4) is the greatest genetic risk factor for Alzheimer's (AD) and is linked to whole-body metabolic dysfunction. However, it is unclear how APOE4 interacts with modifiable factors like diet ...
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Open Access
Avanços recentes em nutrição de larvas de peixes Recent advances in nutrition of fish larval
Article
Article
Luís Eugénio Castanheira da Conceição et al · Sociedade Brasileira de Zootecnia · 2009 · ISSN 1516-3598
Os requisitos nutricionais de larvas de peixes são ainda mal compreendidos, o que leva a altas mortalidades e problemas de qualidade no seu cultivo. Este trabalho pretende fazer uma revisão de novas metodologias de inv...
LCC LCC:Animal cultureIdioma English
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Open Access
Blood cell ratio biomarkers of systemic inflammation in chronic obstructive pulmonary disease
Article
Article
Kaman So et al · BMC · 2026 · ISSN 1465-993X
Abstract Background Blood eosinophil count is an accepted biomarker for type 2 inflammation in COPD. However, the majority of COPD patients are characterized by non-type 2 inflammation. We aimed to test readily obtainabl...
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Extração e análise eletroforética em gel de poliacrilamida (SDS-PAGE) de proteínas totais de folhas e raízes de Piper tuberculatum Extraction and polyacrylamide gels electrophoresis analysis (SDS-PAGE) of total protein from leaves and roots of Piper tuberculatum
Article
Article
Redinaldo dos Santos Silva et al · Instituto Nacional de Pesquisas da Amazônia · 2009 · ISSN 0044-5967
O Estado do Pará é o principal produtor brasileiro de pimenta-do-reino (Piper nigrum Link), entretanto a sua produção tem sido bastante afetada pela doença conhecida como fusariose. O Fusarium solani f. sp. piperis ...
LCC LCC:Science (General)Idioma English
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Identification of candidate biomarkers for diagnosis, disease activity, and relapse prediction in IgG4-related disease
Article
Article
Qiyuan Hao et al · BMC · 2026 · ISSN 1478-6362
Abstract Objectives IgG4-related disease (IgG4-RD) is an immune-mediated condition with diagnostic challenges in clinical practice. Sensitive biomarkers are needed for diagnosis, disease activity and disease progression ...
LCC LCC:Diseases of the musculoskeletal systemIdioma English
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Open Access
Multi-Omics Approaches to Improve Meat Quality and Taste Characteristics
Article
Article
Young-Hwa Hwang et al · Springer Nature · 2023 · ISSN 2636-0772
Abstract With rapid advances in meat science in recent decades, changes in meat quality during the pre-slaughter phase of muscle growth and the post-slaughter process from muscle to meat have been investigated. Commonly ...
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Proteome-assisted multi-feature discriminant modelling of chronic post-surgical pain in female patients: A proof-of-concept study
Article
Article
Simon Haroutounian et al · Elsevier · 2026 · ISSN 1096-1186
Pain after surgery is of major perioperative concern because it is associated with substantial complications, including chronic post-surgical pain (CPSP) development. The CPSP incidence is high, and its accurate predicti...
LCC LCC:Therapeutics. PharmacologyIdioma English
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Open Access
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