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Convergence Properties of the Nelder--Mead Simplex Method in Low Dimensions
Article
Article
Convergence Properties of the Nelder--Mead Simplex Method in Low Dimensions
Jeffrey C. Lagarias; James A. Reeds; Margaret H. Wright; Paul E. Wright · SIAM Journal on Optimization · 1998
Abstract. The Nelder–Mead simplex algorithm, first published in 1965, is an enormously popular direct search method for multidimensional unconstrained minimization. Despite its widespread use, essentially no theoretica...
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Efficient Fuzzy Solutions for Linear Fractional Programming Problems: Using Pentagonal Fuzzy Numbers and the Decomposition Method
Article
Article
Efficient Fuzzy Solutions for Linear Fractional Programming Problems: Using Pentagonal Fuzzy Numbers and the Decomposition Method
Rebaz Mustafa et al · College of science, university of Diyala · 2026 · ISSN 2958-4612
This paper presents an efficient method for solving fully fuzzy linear fractional programming (FFLFP) problems using pentagonal fuzzy numbers (PFNs) and the decomposition method. In real-world decision-making, uncertaint...
LCC TENDOlNjaWVuY2U~Idioma English
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On Some Aspects of the Examination in Econometrics
Article
Article
On Some Aspects of the Examination in Econometrics
Symon Serbenyuk · Vasyl Stefanyk Carpathian National University · 2021 · ISSN 2311-0155
Teaching econometrics has been studied by a number of researchers, however, there is little information available on the quality of examination and on simplification of tests for demonstration the high-quality knowledge ...
LCC TENDOkVkdWNhdGlvbg~~; TENDOkVjb25vbWljcyBhcyBhIHNjaWVuY2U~Idioma English
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Theory of Linear and Integer Programming
Article
Article
Theory of Linear and Integer Programming
Adam N. Letchford; Alexander Schrijver · Journal of the Operational Research Society · 2000
Introduction and Preliminaries. Problems, Algorithms, and Complexity. LINEAR ALGEBRA. Linear Algebra and Complexity. LATTICES AND LINEAR DIOPHANTINE EQUATIONS. Theory of Lattices and Linear Diophantine Equations. Algorit...
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Combinatorial Optimization: Algorithms and Complexity.
Article
Article
Combinatorial Optimization: Algorithms and Complexity.
David Johnson; Christos H. Papadimitriou; Kenneth Steiglitz · American Mathematical Monthly · 1984
This clearly written , mathematically rigorous text includes a novel algorithmic exposition of the simplex method and also discusses the Soviet ellipsoid algorithm for linear programming; efficient algorithms for network...
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The need of social support, life attitudes and life satisfaction among parents of children suffering from epidermolysis bullosa
Article
Article
The need of social support, life attitudes and life satisfaction among parents of children suffering from epidermolysis bullosa
Dorota Mącik et al · Termedia Publishing House · 2015 · ISSN 0033-2526
Introduction. Epidermolysis bullosa (EB) is a group of rare genetic skin disorders. Much is known about the disease from the medical perspective, but there are still only a few studies about the psychological condition ...
LCC LCC:Medicine; LCC:DermatologyIdioma English
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A expressão da proteína p16 e herpes simples vírus tipo 2 em lesões pré-neoplásicas e neoplásicas do colo do útero Immunohistochemical expression of p16 and herpes simplex virus type 2 in squamous intraepithelial lesions and cervical cancer
Article
Article
A expressão da proteína p16 e herpes simples vírus tipo 2 em lesões pré-neoplásicas e neoplásicas do colo do útero Immunohistochemical expression of p16 and herpes simplex virus type 2 in squamous intraepithelial lesions and cervical cancer
Mila de Moura Behar Pontremoli Salcedo et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2008 · ISSN 0100-7203
OBJETIVO: demonstrar a expressão de biomarcadores, detectados por técnicas de imunohistoquímica, em tecidos sadios, lesões pré-neoplásicas e neoplásicas do colo do útero. MÉTODOS: para avaliação da reatividade...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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SGK2 mediates apoptosis in herpes simplex keratitis by suppressing protective autophagy via the mTOR pathway
Article
Article
SGK2 mediates apoptosis in herpes simplex keratitis by suppressing protective autophagy via the mTOR pathway
Suyu Liu et al · BMC · 2026 · ISSN 1743-422X
Abstract Background Herpes simplex virus type 1 (HSV-1) is a common human pathogen of herpes simplex keratitis (HSK), one of the leading causes of infectious blindness worldwide. Antiviral therapies remain limited by the...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma English
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Acridones As Antiviral Agents: Synthesis, Chemical and Biological Properties
Article
Article
Acridones As Antiviral Agents: Synthesis, Chemical and Biological Properties
Sepúlveda, Claudia Soledad et al · Bentham Science Publishers · 2013 · ISSN 2402-2414
Acridones are a class of compounds that have attracted attention in recent years for their wide range of biological properties, including selective inhibition of diverse human pathogenic viruses. The wide spectrum of ant...
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Larvicidal and antioxidant potential of Iranian Propolis against Anisakis simplex L3: A comparative in vitro study with chemical and safety profiling
Article
Article
Larvicidal and antioxidant potential of Iranian Propolis against Anisakis simplex L3: A comparative in vitro study with chemical and safety profiling
Abolghasem Siyadatpanah et al · Veterinary World · 2026 · ISSN 0972-8988
Background and Aim: Anisakis simplex is a zoonotic nematode responsible for anisakidosis in humans, mainly transmitted through the consumption of raw or undercooked marine fish. Increasing resistance to synthetic anthelm...
LCC LCC:Animal culture; TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma English
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Oral health status, treatment needs and oral health-related quality of life in patients with epidermolysis bullosa in Austria: a mixed-methods pilot study
Article
Article
Oral health status, treatment needs and oral health-related quality of life in patients with epidermolysis bullosa in Austria: a mixed-methods pilot study
Sebastián Véliz et al · Frontiers Media S.A · 2026 · ISSN 2673-4842
IntroductionEpidermolysis bullosa (EB) is a rare genetic disease with skin and mucosal fragility. Severe cases present major physical and psychological compromise, contributing to comorbidities and reducing oral health-r...
LCC TENDOkRlbnRpc3RyeQ~~Idioma English
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Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica
Article
Article
Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica
Mandal, Pinaki et al · International Medical Press · 2007 · ISSN 0956-3202
Natural compounds offer interesting pharmacological perspectives for antiviral drug development. In this study, we have analysed sulphated-fucan-containing fractions isolated from the brown seaweed Cystoseira indica. The...
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Detecção de Citomegalovírus Humano e Herpesvírus Simples tipo 2 em amostras cervicais Detection of Human Cytomegalovirus and Herpes Simplex Virus type 2 in cervical sample
Article
Article
Detecção de Citomegalovírus Humano e Herpesvírus Simples tipo 2 em amostras cervicais Detection of Human Cytomegalovirus and Herpes Simplex Virus type 2 in cervical sample
Danielle Albuquerque Pires Rocha et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2012 · ISSN 0100-7203
OBJETIVO: Testar a presença de DNA de Citomegalovírus Humano (HCMV) e Herpesvírus Simples tipo 2 (HSV-2) em amostras cervicais de mulheres atendidas em um serviço de atenção primária à saúde no município de Coa...
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Original papers Herpes simplex virus infection – survey on knowledge of herpes virus infection among people aged 18–35
Article
Article
Original papers Herpes simplex virus infection – survey on knowledge of herpes virus infection among people aged 18–35
Ewelina Biało-Wójcicka et al · Termedia Publishing House · 2015 · ISSN 0033-2526
Introduction . Genital herpes is one of the most common sexually transmitted viral diseases and the most common cause of mucous membrane ulcerations in the genital area. The number of sexually transmitted infections caus...
LCC LCC:Medicine; LCC:DermatologyIdioma English
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Special papers Herpes progenitalis – prevention of herpes simplex virus infections
Article
Article
Special papers Herpes progenitalis – prevention of herpes simplex virus infections
Ewelina Biało-Wójcicka et al · Termedia Publishing House · 2015 · ISSN 0033-2526
Genital herpes is one of the most common sexually transmitted viral diseases and the most common cause of mucosal erosions and ulcerations in the genital area. According to epidemiological data, the infection caused by g...
LCC LCC:Medicine; LCC:DermatologyIdioma English
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Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols
Article
Article
Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols
Ugliarolo, Esteban Ariel et al · Pergamon-Elsevier Science Ltd · 2012 · ISSN 5986-5991
New chiral purinyl and 8-azapurinyl carbanucleoside derivatives based on indanol were synthesized from commercial available (1S,2S)-trans-1-amino-2-indanol and (1R,2R)-trans-1-amino-2-indanol using a linear methodology. ...
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Bioresource Management Via Least Cost Feed Formulation for Red Tilapia (Oreochromis Sp.): Application of Linear Programming Technique
Article
Article
Bioresource Management Via Least Cost Feed Formulation for Red Tilapia (Oreochromis Sp.): Application of Linear Programming Technique
Boudjema Kamel et al · Wright State University · 2024 · ISSN 2309-3854
The method of linear programming (LP) was utilized to determine the relationship between the composition of nutrients of each ingredients, specifications for raw materials, cost and requirements for nutrients of the red ...
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~; TENDOkVjb2xvZ3k~Idioma English
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Case Report: Beyond conventional diagnostics: mNGS support in a complex immunocompromised patient diagnosis
Article
Article
Case Report: Beyond conventional diagnostics: mNGS support in a complex immunocompromised patient diagnosis
Rossana Scutari et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
Next-generation metagenomic sequencing (mNGS) enables the direct and unbiased detection of pathogens from clinical samples, overcoming the limitations of standard methods. It is particularly valuable in immunocompromised...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma English
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Hidropisia fetal não imune: experiência de duas décadas num hospital universitário Nonimmune hydrops fetalis: two decades of experience in a university hospital
Article
Article
Hidropisia fetal não imune: experiência de duas décadas num hospital universitário Nonimmune hydrops fetalis: two decades of experience in a university hospital
Alessandra Fritsch et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2012 · ISSN 0100-7203
OBJETIVO: Identificar a etiologia da hidropisia fetal não imune em gestantes diagnosticadas e encaminhadas para acompanhamento pré-natal. MÉTODOS: Estudo retrospectivo com análise dos casos de hidropisia fetal não i...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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Optimization of Span 80-Croduret 50-Propylene Glycol as Emulsifier of Dried Strawberry Juice (Fragaria vesca L.) Emulgel and Permeation Test Through Shed Snakeskin Membrane
Article
Article
Optimization of Span 80-Croduret 50-Propylene Glycol as Emulsifier of Dried Strawberry Juice (Fragaria vesca L.) Emulgel and Permeation Test Through Shed Snakeskin Membrane
Dian Eka Ermawati et al · Universitas Gadjah Mada · 2026 · ISSN 1410-5918
Strawberry is a natural source of antioxidants with potential to inhibit melanin production in the skin. However, its application in topical formulations is limited by factors such as stability, skin permeability, and ef...
LCC LCC:MedicineIdioma English
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Scalable and reliable multi-agent reinforcement learning for traffic assignment
Article
Article
Scalable and reliable multi-agent reinforcement learning for traffic assignment
Leizhen Wang et al · Tsinghua University Press · 2025 · ISSN 2772-4247
The evolution of metropolitan cities and increasing travel demand impose stringent requirements on traffic assignment methods. Multi-agent reinforcement learning (MARL) approaches outperform traditional methods in modeli...
LCC LCC:Transportation engineeringIdioma English
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A Simplex Method for Function Minimization
Article
Article
A Simplex Method for Function Minimization
J. A. Nelder; R. Mead · The Computer Journal · 1965
A method is described for the minimization of a function of n variables, which depends on the comparison of function values at the (n + 1) vertices of a general simplex, followed by the replacement of the vertex with the...
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Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide
Article
Article
Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide
Bellini, María José et al · SEDICI UNLP · 2011
Background: Insulin-like growth factor-I (IGF-I) exerts neuroprotective actions in the central nervous system that are mediated at least in part by control of activation of astrocytes. In this study we have assessed the ...
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High Incidence of Herpes Simplex Virus-1 in Cord Blood and Placenta Infection of Women in Southern Brazil
Article
Article
High Incidence of Herpes Simplex Virus-1 in Cord Blood and Placenta Infection of Women in Southern Brazil
Emiliana Claro Avila et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2020 · ISSN 0100-7203
Abstract Objective Estimate the prevalence of human herpesvirus type 1 HSV-1 DNA in placental samples, its incidence in umbilical cord blood of newborns and the associated risk factors. Methods Placental biopsies and...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma English
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