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Abstract. With levels of medicine and pharmacology individualization constantly increasing, the scientific community is becoming seriously concerned about the safety of existing and developing drugs for the pediatric pop...

Abstract Traditional medicinal plants play a crucial role in paediatric healthcare, especially in underdeveloped countries where access to modern medicine is limited. This review synthesizes ethnobotanical, pharmacologic...

Triclosan (TCS) is widely applied to daily necessities as a chemical bacteriostatic agent. Environmental TCS levels have increased significantly following the coronavirus disease 2019 pandemic, posing a potential threat ...

Abstract Assessment of the toxicity of insoluble particulate matter (PM) in the atmosphere is crucially important. However, because of challenges associated with extracting insoluble PM from filters, the toxicity of inso...

Tanniferous plants represent a promising alternative for controlling gastrointestinal nematodes of small ruminants. This experiment evaluated the effects of extracts from the leaf and stem of Anadenanthera colubrina, Leu...

ABSTRACT Pseudanabaena galeata, a well-known toxin-producer, is commonly found in water supplies. In order to assess potential risks associated with oral exposure to this cyanobacterium, mouse toxicological studies were ...

Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of citric acid anhydrous and citric acid monohydrate produced by fermentation with Aspe...

Fuzi, the processed lateral root of Aconitum carmichaelii Debeaux (Ranunculaceae), is a vital yet highly toxic botanical drug in traditional Chinese medicine. However, its narrow therapeutic window, driven by highly toxi...

El D-003 es una mezcla de ácidos alifáticos primarios de muy alto peso molecular purificada de la cera de caña, con efectos hipolipemiante y antiagregante plaquetario demostrados experimental y clí- nicamente. Los es...

IntroductionVirtual control groups (VCGs) are proposed as a means to reduce reliance on live animals in preclinical toxicology studies. Despite the potential benefits of VCGs, concerns remain regarding their comparabilit...

Background and Aim: Effective disinfection is critical for controlling pathogenic and opportunistic microorganisms in livestock environments. Didecyldimethylammonium chloride (DDAC), a quaternary ammonium compound, is wi...

Abstract Objective Atomoxetine is widely used in the treatment of attention deficit hyperactivity disorder (ADHD), offering reduced risks of adverse motor effects and chemical dependence. However, its pharmacokinetic p...

In this study, the content of Pb, the physico-chemical and biological parameters in soils, and the metal transfer to vegetative and reproductive Sorghum bicolor plants were evaluated along with their relationship with th...

A few years ago, the 2-hydroxy-4´-methoxy dibenzoylmethane (DBM11) molecule was synthesized and studied as a replacement for avobenzone (AVB, butyl methoxydibenzoylmethane) because of the latter's instability under UVA ...

Abstract Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants of global concern due to their widespread occurrence, environmental persistence, and well-documented adverse effects on human health. In ...

The parenteral administration of antivenoms is the cornerstone of snakebite envenoming therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are available world-wide. We address the main iss...

ObjectiveTo assess the quality of the literature related to the carcinogenicity of perfluorooctane sulfonic acid （PFOS） using the weight of evidence method， and to evaluate its carcinogenic risk through the dose-re...

ABSTRACT The avian embryo is a time-honored animal model for understanding vertebrate development. A key area of extensive study using bird embryos centers on developmental phenotypic plasticity of the cardio-respiratory...

Abstract The Panel on Food Additives and Flavourings (FAF) of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on...

ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and...

ObjectiveTo systematically evaluate the toxic effects and potential health hazards of butyl benzyl phthalate （BBP）， thereby providing a scientific basis for its risk management and control.MethodsLiterature publish...

In the last years, functional foods have awakened consumer, scientific and business interest. A commonly found vegetable in such kind of foods includes garlic (Allium sativum). By its ability for selenium (Se) bio-accumu...