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Abstract The research aimed to study the effect of Diols on modification of an asphaltic materials which could be used as a binder for paving material obtained from Qaiyarah asphalt. 0.5-5 wt.% of Diols (ethylene glycol ...

137Cs can be an important environmental contaminant due to fallout from nuclear reactor accidents and atomic weapons testing. Its contribution to the air gamma dose rate at 1 m height above contaminated ground depends on...

The long-standing view that idioms are formally and thus also semantically fixed has been challenged and many studies have shown that idioms are indeed flexible both structurally and semantically to varying degrees. We o...

Abstract The logical formalization of sentences containing adverbial modification, e.g., “John walks slowly”, remains demanding. According to Bennett (1988, 2002), as facts are exemplifications of properties, they ar...

Abstract Laryngeal cancer (LC) is one of the malignant tumors affecting the head and neck region. 5-methylcytosine (m5C) is a common RNA modification that contributes to the carcinogenesis process. Aly/REF export factor ...

Background and Aim: Adherences to fluid restriction and dietary and medication guidelines are essential for adequate management of hemodialysis patients. This study aimed to assess adherence of dietary modification for...

The text focuses on a critical reflection on research conducted among Czech bodyhackers and, in general, on the possibilities and limitations of the conceptualization of the body, which is a product of technohuman interc...

Abstract Background Covalent protein modification by drugs or their reactive metabolites has emerged as an important mechanism underlying pharmacological activity. However, its contribution to the therapeutic effects of ...

Abstract Background Neuroinflammation following intracerebral hemorrhage (ICH) is a critical contributor to secondary brain injury. Lactylation modification, a novel epigenetic regulatory mechanism, may participate in pa...

Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPis) are the standard of care for primary ovarian cancer (OC), yet adverse events (AEs) frequently necessitate dose modifications. The prognostic impact of ...

Objective: Periodontitis is a chronic inflammatory disease that severely affects oral and general health. N7-methylguanosine (m7G) methylation plays critical roles in regulating gene expression and cellular functions. Me...

Abstract Background Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype of non-Hodgkin lymphoma. Fatty acid synthase (FASN) is a key lipogenic enzyme implicated in tumor progression, but its regulation in DLBC...

This work reports an investigation of the surface modifications induced by irradiation with nanosecondlaser pulses of ultraviolet and visible wavelengths on crosslinked hydrophilic co-polymeric materi-als, which have bee...

Glucocorticoids (GCs), the most downstream effectors of the hypothalamic-pituitary-adrenal (HPA) axis, are key mediators in the interaction between immune and neuroendocrine systems. They exert their biological actions m...

Abstract Histone modifications and chromatin‐binding proteins play crucial roles in regulating gene expression in eukaryotes, with significant implications for fungal pathogenicity and development. However, profiling t...

Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) stands as the most widespread chronic liver disorder globally. Histone β-hydroxybutyrylation (Kbhb)—a novel post-translational modif...

Alteration of maxillary growth, improvement in mandibular growth and position, and change in dental and muscular relationships, especially changing in esthetic profile are the expected results of myofunctional appliances...

ObjectiveSuperfine cement-based grouting materials generally suffer from limitations including high bleeding rates, unfavourable rheological properties, poor stability, and strength retrogression. These issues can be mit...

Photosensitized reactions mediated by endogenous chromophores have been associated with the etiology of age-related cataract disease. Endogenous chromophores such as 3-hydroxykynurenine (3OHKN) can be found in both free ...

Background: Nucleosomes are the building blocks of chromatin where gene regulation takes place. Chromatin landscapes have been profiled for several species, providing insights into the fundamental mechanisms of chromatin...

Objectives Promoting regular physical activity (PA) is essential in cardiac rehabilitation; yet many patients exhibit low levels of PA. In January 2022, the Improving Physical Activity (IMPACT) trial, a randomised contro...

Prenatal exposure to fine particulate matter (PM2.5) has been associated to childhood atopic dermatitis (AD), but the critical exposure window and the role of maternal inflammatory pathways remain unclear. We analyzed 40...

Introduction: Attentional bias, the tendency that a person has to drive or maintain attention to a specific class of stimuli, may play an important role in the etiology and persistence of mental disorders. Attentional b...

Abstract The massive production of plastics, together with inadequate waste management, has intensified the problem of plastic pollution. Recently, the scientific community has increasingly investigated the interactions ...