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Accurate normalization is an absolute prerequisite for correct measurement of gene expression. For quantitative real-time reverse transcription-PCR (RT-PCR), the most commonly used normalization strategy involves standar...

MOTIVATION: When running experiments that involve multiple high density oligonucleotide arrays, it is important to remove sources of variation between arrays of non-biological origin. Normalization is a process for reduc...

The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq is likely to become the platform of choice for interrogating steady state RNA. In order to discover biologically important changes ...

Protein quantification without isotopic labels has been a long-standing interest in the proteomics field. However, accurate and robust proteome-wide quantification with label-free approaches remains a challenge. We devel...

BACKGROUND: Gene-expression analysis is increasingly important in biological research, with real-time reverse transcription PCR (RT-PCR) becoming the method of choice for high-throughput and accurate expression profiling...

In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip system with the objective of improving upon currently used measures of gene expression. Our analyses ma...

This paper describes an exercise in generic data normalization theory using a data reification calculus base on the categorial approach to datatypes. We develop a relational data model in a functional language and then ...

Component Based Software Development (CBSD) is a development process based on components’ reuse. One of the main difficulties for developers is selecting the most suitable component that fit in their development system...

Objetivos - Obtener la información del procedimiento de soldeo por arco bajo gas protector con electrodo consumible, para seleccionar los materiales, los equipos o las herramientas, entre otros, interpretando las especi...

Abstract. The pumping activity permanently carried out by the heart requires a constant energy supply that is derived mainly from fatty acids and, to a lesser extent, from glucose and lactate. The Krebs cycle plays a cen...

"The Repertory Grid method is widely used in knowledge engineering to infer functional relationships between constructs given by an expert. The method is ignoring information that could be used to infer more precise dep...

Artículo de publicación ISI Recent intensive Swift monitoring of the Seyfert 1 galaxy NGC 5548 yielded 282 usable epochs over 125 days across six UV/optical bands and the X-rays. This is the densest extended active gal...

This paper presents FPGA implementations of classical algorithms for computing ln(x) with some improvement at the level of the multiplication steps, and step skipping techniques. One starts from a practical implementatio...

This paper reports on an optimum dynamic progxamming (DP) based time-normalization algorithm for spoken word recognition. First, a general principle of time-normalization is given using time-warping function. Then, two t...

We present measurements of dust reddening using the colors of stars with spectra in the Sloan Digital Sky Survey. We measure reddening as the difference between the measured and predicted colors of a star, as derived fro...

Abstract Summary: MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252 Gbps in 44.1 and 9...

A variant of the popular nonparametric nonuniform intensity normalization (N3) algorithm is proposed for bias field correction. Given the superb performance of N3 and its public availability, it has been the subject of s...

La información extraída de especimenes biológicos es inherentemente tridimensional. Los datos tridimensionales (3D) permiten un mejor entendimiento de las estructuras y los eventos biológicos, comparados con sus proy...

Abstract Introduction: synchronic stenosis of the common and internal carotid artery is a rare condition behaving as a hemodynamic pseudo-oclusion of the intracranial carotid artery. Case report: we report an unusual c...

With the shift towards a more sustainable energy system, the need for a better understanding of the behavior development over time of consumers and prosumers arises. Despite the growing penetration of smart meter infrast...

A quantum version of the Monty Hall problem, based upon the Positive Operator Valued Measures (POVM) formalism, is proposed. It is shown that basic normalization and symmetry arguments lead univocally to the associated P...

The discriminative model learning for image denoising has been recently attracting considerable attentions due to its favorable denoising performance. In this paper, we take one step forward by investigating the construc...

As new drugs are developed, it is essential to appropriately translate the drug dosage from one animal species to another. A misunderstanding appears to exist regarding the appropriate method for allometric dose translat...

(Abridged) The WMAP 5-year data strongly limit deviations from the minimal LCDM model. We constrain the physics of inflation via Gaussianity, adiabaticity, the power spectrum shape, gravitational waves, and spatial curva...