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Advances in perinatal and neonatal medicine have dramatically improved the survival rates of infants with perinatal vulnerabilities of preterm birth (PTB), low birth weight (LBW) or small for gestational age (SGA), by re...

Craniofacial morphogenesis is a highly coordinated developmental process governed by complex genetic and molecular interactions. Among these, the PAX family of transcription factors plays a pivotal role in the regulation...

Abstract Little is known about the regulation and function of phase separation in craniofacial developmental disorders. MSX1 mutations are associated with human cleft palate, the most common craniofacial birth defect. He...

Nonsyndromic orofacial clefts (NSOC) are common congenital craniofacial developmental defects. Current evidence suggests that genetic factors, environmental exposures, and their interactions jointly contribute to the dev...

Bisphenol A (BPA) can combine with glycidyl methacrylate to form bisphenol A glycidyl methacrylate (Bis-GMA). Bis-GMA is an important industrial raw material and a significant component of dental resin materials. Althoug...

Introduction and aims: Submucous cleft palate (SMCP) is a congenital craniofacial malformation. While TBX22 is a known pathogenic gene, the potential role of TBX15 in SMCP remains unclear. This study aimed to investigate...

HELIOS is an IKAROS-family zinc-finger transcription factor that plays an important role in regulatory T cell function and conventional T cell homoeostasis. HELIOS shares a conserved N-terminal DNA-binding and C-terminal...

Cleft lip and palate are the most common craniofacial anomalies in Indonesia. Recent publications report that there was delayed skeletal and dental age in cleft lip and palate patients. Panoramic and lateral cephalometri...

Abstract Parathyroid hormone 1 receptor (PTH1R) signaling is critical for mineral ion homeostasis and skeletal development. Although its role in tooth root formation and eruption is established, its specific functions in...

Latar Belakang. Penglihatan merupakan salah satu faktor yang diperlukan untuk mengontrol postur kepala. Postur kepala berhubungan dengan kompleks kraniofasial. Maksila dan mandibula merupakan bagian dari kompleks kraniof...