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23 risultati trovati.

Tipi di risorsa: Libro cartaceo Libro elettronico Articolo Rivista Tesi Capitolo
Ricerca accademica
The Evolution of Gene Sequencing Technologies: Unveiling Genetic Architecture of Nonsyndromic Orofacial Clefts
Articolo
Articolo
The Evolution of Gene Sequencing Technologies: Unveiling Genetic Architecture of Nonsyndromic Orofacial Clefts
Haolang Zhao et al · Wiley · 2026 · ISSN 1469-5073
Nonsyndromic orofacial clefts (NSOC) are common congenital craniofacial developmental defects. Current evidence suggests that genetic factors, environmental exposures, and their interactions jointly contribute to the dev...
LCC LCC:GeneticsIdioma Inglés
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Open Access
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Guía para la integración de las TIC en el aula de idiomas
Libro elettronico
Libro elettronico
Guía para la integración de las TIC en el aula de idiomas
Dominguez Miguela, Antonia; Fernández Santiago, Miriam · Universidad de Huelva · 2006 · ISBN 9788417288006
La presente guía pretende ser un instrumento sencillo de conocimiento general de los medios, herramientas y posibilidades que las nuevas tecnologías de la información y la comunicación (TICs) ofrecen a los y las doce...
Idioma Español
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Institucional
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Fabrications, Applications and Challenges of Solid-state Nanopores: A Mini Review
Articolo
Articolo
Fabrications, Applications and Challenges of Solid-state Nanopores: A Mini Review
Zifan Tang et al · SAGE Publishing · 2016 · ISSN 1847-9804
Nanopore sensors are expected to be one of the most promising next generation sequencing technologies, with label-free, amplification-free and high-throughput fea‐ tures, as well as rapid detections and low cost. Solid...
LCC LCC:Materials of engineering and construction. Mechanics of materials; TENDOlRlY2hub2xvZ3k~Idioma Inglés
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A ribose world: Current status and future challenges of plant RNA biology
Articolo
Articolo
A ribose world: Current status and future challenges of plant RNA biology
Marquardt, Sebastian et al · Oxford University Press · 2023 · ISSN 2203-2207
Elucidation of the cellular functions of RNAs represents one of the most exciting research areas in modern life sciences. RNAs play crucial roles in plant biology, including developmental regulation and environmental res...
Idioma Inglés
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Alternative splicing in human cells exposed to ionizing radiation: a comprehensive review of ex vivo and in vivo studies
Articolo
Articolo
Alternative splicing in human cells exposed to ionizing radiation: a comprehensive review of ex vivo and in vivo studies
Leberle, Jeronimo Hector et al · Taylor & Francis Ltd · 2025 · ISSN 0955-3002
Purpose: This study reviews how ionizing radiation (IR) induces alternative splicing (AS) in non-tumor and tumor cells under both ex vivo and in vivo irradiation conditions. The relevance and limitations of IR-induced AS...
Idioma Inglés
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Chromosome-level genome assembly reveals the genetic mechanisms underlying elite waterlogging tolerance in Actinidia rufa
Articolo
Articolo
Chromosome-level genome assembly reveals the genetic mechanisms underlying elite waterlogging tolerance in Actinidia rufa
Qiong Zhang et al · Springer · 2026 · ISSN 2948-1104
Abstract Actinidia rufa is a valuable species for hybridization and introgressive breeding of new kiwifruit cultivars due to its exceptional tolerance to waterlogging. In this study, a chromosome-level genome of A. rufa ...
LCC TENDOlBsYW50IGN1bHR1cmU~Idioma Inglés
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Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage
Articolo
Articolo
Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage
Andreas L. Gimpel et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Many codecs with different error-correction approaches have been implemented for DNA data storage to date. However, no studies have systematically benchmarked codec implementations to establish their current sta...
LCC TENDOlNjaWVuY2U~Idioma Inglés
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Genetic Prediction of Sepsis Severity Based on the Detection of MCP-1 Gene Polymorphism in Patients with Acquired Immunological Disorders
Articolo
Articolo
Genetic Prediction of Sepsis Severity Based on the Detection of MCP-1 Gene Polymorphism in Patients with Acquired Immunological Disorders
N. Matselski et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background and AimsAcquired immunodeficiency in patients with hematological oncology is a serious and common complication, significantly impacting prognosis and quality of life. High doses of cytostatic drugs and the mal...
LCC LCC:Immunologic diseases. AllergyIdioma Inglés
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Guiding the global evolution of cytogenetic testing for hematologic malignancies
Articolo
Articolo
Guiding the global evolution of cytogenetic testing for hematologic malignancies
Akkari, Yassmine M.N. et al · American Society of Hematology · 2022 · ISSN 2273-2284
Cytogenetics has long represented a critical component in the clinical evaluation of hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot of genome-wide copy number and structural variatio...
Idioma Inglés
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Haplotype determination of the upstream regulatory region and the second exon of the BoLA-DRB3 gene in Holstein cattle
Articolo
Articolo
Haplotype determination of the upstream regulatory region and the second exon of the BoLA-DRB3 gene in Holstein cattle
Goszczynski, Daniel Estanislao et al · Wiley Blackwell Publishing, Inc · 2014 · ISSN 0001-2815
Polymorphisms of the BoLA-DRB3 gene are located primarily in the second exon [antigen binding site (ABS)] and, to a lesser extent, in the upstream regulatory region (URR). It can be hypothesised that exon 2 and the URR a...
Idioma Inglés
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Invited review: Novel methods and perspectives for modulating the rumen microbiome through selective breeding as a means to improve complex traits: Implications for methane emissions in cattle
Articolo
Articolo
Invited review: Novel methods and perspectives for modulating the rumen microbiome through selective breeding as a means to improve complex traits: Implications for methane emissions in cattle
González Recio, Oscar et al · Universidad de Costa Rica · 2023 · ISSN 1871-1413
The rumen microbiome is responsible for methane emission in ruminants. The study of microbes in the rumen has attracted great interest in the last decade. High-throughput sequencing technologies have been key in expandin...
Idioma Inglés
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Recent developments in nucleic acid based techniques for use in rumen manipulation
Articolo
Articolo
Recent developments in nucleic acid based techniques for use in rumen manipulation
Christopher McSweeney et al · Sociedade Brasileira de Zootecnia · 2009 · ISSN 1516-3598
Nucleic acid-based techniques which can be used to characterise complex microbial communities without incubation are now being employed regularly in ruminant nutrition studies. Conventional culture-based methods for enum...
LCC LCC:Animal cultureIdioma Inglés
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Reconsidering rumen microbial consortia to enhance feed efficiency and reduce environmental impact of ruminant livestock production systems Consórcios microbianos no rúmen para melhorar a eficiência alimentar e reduzir o impacto ambiental dos sistemas de produção animal
Articolo
Articolo
Reconsidering rumen microbial consortia to enhance feed efficiency and reduce environmental impact of ruminant livestock production systems Consórcios microbianos no rúmen para melhorar a eficiência alimentar e reduzir o impacto ambiental dos sistemas de produção animal
Jeffrey Lynn Firkins · Sociedade Brasileira de Zootecnia · 2010 · ISSN 1516-3598
Because cultivation-based approaches to assess rumen microbiology assess only the minority of microbial groups and can miss opportunities to assess important functions, molecular-based approaches have flourished in micro...
LCC LCC:Animal cultureIdioma Inglés
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mist: a hierarchical Bayesian framework for detecting differential DNA methylation dynamics in single-cell data
Articolo
Articolo
mist: a hierarchical Bayesian framework for detecting differential DNA methylation dynamics in single-cell data
Daoyu Duan et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Recent advancements in single-cell DNA methylation (scDNAm) sequencing technologies have enabled the profiling of epigenetic landscapes at unprecedented resolution, offering insights into cellular heterogeneity,...
LCC TENDOlNjaWVuY2U~Idioma Inglés
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Diagnostic Yield and Advantages of Exome/Genome Sequencing in Inborn Errors of Immunity
Articolo
Articolo
Diagnostic Yield and Advantages of Exome/Genome Sequencing in Inborn Errors of Immunity
Bobbi McGivern et al · Rockefeller University Press · 2026 · ISSN 3065-8993
The rapid annual increase in conditions classified as inborn errors of immunity (IEI), along with associated genetic variants, creates diagnostic challenges. The comprehensive nature of exome sequencing (ES) and genome s...
LCC LCC:Immunologic diseases. AllergyIdioma Inglés
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Association between molecular and quantitative variability in a tomato broad cross identified by sequence-specific markers developed from transcriptomic polymorphism for the sHSP cluster in chromosome six
Articolo
Articolo
Association between molecular and quantitative variability in a tomato broad cross identified by sequence-specific markers developed from transcriptomic polymorphism for the sHSP cluster in chromosome six
Cacchiarelli, Paolo et al · Springer · 2026 · ISSN 0925-9864
Advances in plant sequencing have revolutionized breeding strategies, but implementing them in large-scale programs remains expensive. A more practical strategy uses genomic and transcriptomic data from parental lines to...
Idioma Inglés
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Integrative transcriptomic profiling reveals molecular signatures of disease progression from gastroesophageal reflux disease to Barrett's esophagus: A foundation for single-cell resolution studies
Articolo
Articolo
Integrative transcriptomic profiling reveals molecular signatures of disease progression from gastroesophageal reflux disease to Barrett's esophagus: A foundation for single-cell resolution studies
Shanshan Jiang et al · Elsevier · 2026 · ISSN 2472-6303
Background: Barrett's esophagus (BE) represents a critical precancerous lesion arising from chronic gastroesophageal reflux disease (GERD), with significant risk of progression to esophageal adenocarcinoma. Despite advan...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma Inglés
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Ancient Human Mitogenome of the Beagle Channel (Tierra del Fuego): An Argentine Collaborative Project
Articolo
Articolo
Ancient Human Mitogenome of the Beagle Channel (Tierra del Fuego): An Argentine Collaborative Project
Arencibia, Valeria et al · Cambridge University Press · 2023 · ISSN 1045-6635
The increasing use of massively parallel sequencing in the study of current and ancient human populationshas enabled new approaches to bioanthropological and archaeological issues; however, its application toarchaeologic...
Idioma Inglés
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Cherry microbiota and metabolites with planting altitude of Coffea arabica in Baoshan of China
Articolo
Articolo
Cherry microbiota and metabolites with planting altitude of Coffea arabica in Baoshan of China
Xiaojing Shen et al · Frontiers Media S.A · 2026 · ISSN 2296-861X
The planting altitude of coffee is one of the important influencing factors on coffee quality. The effects of four planting altitudes (1,000 m, AT1; 1,200 m, AT2; 1,400 m, AT3; and 1,600 m, AT4) on the microorgan...
LCC LCC:Nutrition. Foods and food supplyIdioma Inglés
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Presence of bacterial DNA in synovial fluid from the temporomandibular joint in patients with temporomandibular joint disorders
Articolo
Articolo
Presence of bacterial DNA in synovial fluid from the temporomandibular joint in patients with temporomandibular joint disorders
Nikoo Bazsefidpay et al · Frontiers Media S.A · 2026 · ISSN 2673-4842
IntroductionTemporomandibular joint disorders (TMJD) are common, affecting approximately 30% of the population. While the aetiology of TMJD has been considerably discussed, one aspect that has not been thoroughly investi...
LCC TENDOkRlbnRpc3RyeQ~~Idioma Inglés
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Proteome-wide prediction of the functional impact of missense variants with ProteoCast
Articolo
Articolo
Proteome-wide prediction of the functional impact of missense variants with ProteoCast
Marina Abakarova et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Dissecting the functional impact of genetic mutations is essential to advancing our understanding of genotype-phenotype relationships and identifying therapeutic targets. Despite progress in sequencing and genom...
LCC TENDOlNjaWVuY2U~Idioma Inglés
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Treatment of Germline TET2 Deficiency with a Hypomethylating Agent
Articolo
Articolo
Treatment of Germline TET2 Deficiency with a Hypomethylating Agent
Cheryl A.C. Peretz et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Clinical PresentationPatients with germline TET2 loss of function exhibit a syndrome of immunodeficiency, autoimmune lymphoproliferation, developmental delay, and predisposition to lymphoma. An 8-week-old infant was admi...
LCC LCC:Immunologic diseases. AllergyIdioma Inglés
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Multimodal framework for the joint analysis of single-cell RNA and T cell receptor sequencing data predicts T cell response to cancer immunotherapy
Articolo
Articolo
Multimodal framework for the joint analysis of single-cell RNA and T cell receptor sequencing data predicts T cell response to cancer immunotherapy
Chujun He et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract T cell states are prognostic in different cancer types. Recent technologies enable joint profiling of T cell RNA and T cell receptor (TCR) sequences at single-cell resolution. Here we present the TCR-RNA Integra...
LCC TENDOlNjaWVuY2U~Idioma Inglés
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