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Abstract A key factor contributing to the success of Darwin and Wallace’s theory of biological evolution by natural selection was its population-level perspective. This conceptual framework was not immediately adopted,...

Abstract The modification of jets by interaction with the quark gluon plasma has been extensively established through the comparison of observables computed for samples of jets produced in nucleus-nucleus collisions and ...

Autoimmune rheumatic diseases (ARDs), often characterized by pain, constitute a diverse group of autoimmune conditions involving inflammation-mediated injuries to bones, joints, surrounding connective tissues, and occasi...

Recent studies have shown that the presence of an RNA modification, N6-methyladenosine (m6A), in viral RNAs during infection significantly impacts the outcome of viral replication and pathogenesis. In particular, various...

The structure of mercury-modified amorphous films of the Se-Sb system was studied using the methods of X-ray diffractometry and Raman spectroscopy. It was ascertained that the structure of the phase that formed in the am...

Using the method of low-temperature nitrogen adsorption/desorption, the porous structure of nanoporous carbon materials obtained by alkaline activation of light industry waste (walnut shells) with subsequent thermal modi...

Abstract N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA and plays a crucial role in post-transcriptional gene regulation. Recent studies have revealed that m6A modification is dysr...

"We discuss a modification of the evolutionary minority game (EMG) in which agents are placed in the nodes of a regular or a random graph. A neighborhood for each agent can thus be defined and a modification of the usual...

Abstract Objectives The objectives of this study were: (1) to compare the incidence of effective orifice area (EOA) after either the trans-catheter and surgical aortic valve replacement (SAVR); and (2) to assess the impa...

Abstract Background Prostate cancer (PCa) is a common malignant tumor in men, with a high incidence rate, posing a serious threat to human health and quality of life. Neddylation is a major post-translation modification,...

Antimicrobial resistance represents a major global health challenge, particularly in the context of multidrug-resistant bacteria. Although conventional antibiotics and antimicrobial peptides (AMPs) both exert selective p...

Abstract Proper regulation of ribosome biogenesis is essential for stem cell function and tissue homeostasis, yet its upstream control in adult intestinal stem cells (ISCs) remains unclear. Here, we identify the WD repea...

BACKGROUND: Serum creatinine concentration is widely used as an index of renal function, but this concentration is affected by factors other than glomerular filtration rate (GFR). OBJECTIVE: To develop an equation to pre...

The main objective of this work was to obtain biodegradable nancomposites from polycaprolactone and bentonite with optimized mechanical properties by the chemical modification of the clay (cation exchange reactions). Fir...

In the course of investigating structural modifications of the 3-,4-connected net known as the Pt3O4 structure-type (waserite), a novel 4-,8-connected structure-type was discovered. This lattice is generated by replacing...

En este artículo estudiamos la construcción de la frontera del río Salado del Norte en Santiago del Estero, un espacio pensado como un escenario multidimensional cuyo análisis requiere incorporar variables sociopolí...

El objetivo general de este trabajo es, desde una perspectiva bioarqueológica, aproximarse a los modos de vida de los cazadores recolectores a partir del análisis de las actividades físicas cotidianas. Específicament...

En este trabajo se procede a evaluar las prácticas deformatorias de cráneo en cada una de las sociedades portadoras de los complejos cerámicos característicos del período alfarero en Santiago del Estero. Para tal pr...

"A partir de la necesidad de evitar el vuelco de calidades deficientes de los efluentes, se plantea una optimización de la planta de tratamiento de efluentes líquidos. Para este caso, se ha seleccionado una planta indu...

BACKGROUND: Equations to estimate glomerular filtration rate (GFR) are routinely used to assess kidney function. Current equations have limited precision and systematically underestimate measured GFR at higher values. OB...

A new software suite, called Crystallography & NMR System (CNS), has been developed for macromolecular structure determination by X-ray crystallography or solution nuclear magnetic resonance (NMR) spectroscopy. In contra...

OBJECTIVE: To determine the incidence, cost, and outcome of severe sepsis in the United States. DESIGN: Observational cohort study. SETTING: All nonfederal hospitals (n = 847) in seven U.S. states. PATIENTS: All patients...

The reference human genome sequence set the stage for studies of genetic variation and its association with human disease, but epigenomic studies lack a similar reference. To address this need, the NIH Roadmap Epigenomic...

The purpose of model selection algorithms such as All Subsets, Forward Selection and Backward Elimination is to choose a linear model on the basis of the same set of data to which the model will be applied. Typically we ...