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The rise of influencer marketing reflects how globalization is reshaping digital marketing strategies worldwide. Yet its intersection with cultural and religious values remains underexplored, particularly in Saudi Arabia...

This study aimed to explore the effects of lycopene (LYC) on testicular and sperm damage induced by heat stress in male rats and its potential protective mechanism. Male rats were gavaged with lycopene, and their scrotum...

The main obstacle of influenza is that only a small proportion of cases progress to severe disease due to massive viral replication and excessive immune responses, while effective therapeutics for influenza-induced pneum...

ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Background: Emerging evidence has shown that exposure to polycyclic aromatic hydrocarbons (PAHs) is a risk factor for rheumatoid arthritis (RA). Benzo[a]pyrene (BaP), a representative PAH congener, exacerbates the develo...

ABSTRACT: Objective: While diabetes is known to impair dentin regenerative capacity, the specific role of endothelial nitric oxide synthase (eNOS) is poorly defined. This study aimed to elucidate how eNOS regulates the ...

ABSTRACT: Background: Anoikis plays an important role in cancer metastasis. Nevertheless, research that focuses on the prognostic values of anoikis-related genes (ARGs) in oral squamous cell carcinoma (OSCC) is still sc...

Objective: Periodontally accelerated osteogenic orthodontics (PAOO) combines selective alveolar decortication with orthodontic force to accelerate tooth movement, but its influence on the gingival crevicular fluid (GCF) ...

Bone metastasis is a frequent and incurable consequence of advanced prostate cancer (PC). This process originates through an interplay between disseminated tumor cells and heterogeneous bone resident cells in the metasta...

Introduction and aims: Human dental pulp stem cells (hDPSCs) play pivotal roles in the regeneration of pulp-dentin complex, yet their odontogenic differentiation is critically modulated by the inflammatory microenvironme...

Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...

Introduction and aims: Interleukin (IL)-38 has been identified as an anti-inflammatory cytokine; however, its specific role in temporomandibular joint (TMJ) synovial inflammation and the identity of its functional recept...

Hepatic manifestations of type 2 diabetes, including steatosis, represent a major complication driven by hepatic lipotoxicity and ceramide accumulation, yet few targeted interventions are available. This study investigat...