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Natural language understanding systems require a knowledge base provided with formal representations reflecting the structure of human beings' cognitive system. Although surface semantics can be sufficient in some other ...

Digital technologies have revolutionized studying, analyzing, and interpreting human culture, history, and society. Digital humanities (DH) combine traditional disciplines such as literature, history, and philosophy with...

A flexible statistical framework is developed for the analysis of read counts from RNA-Seq gene expression studies. It provides the ability to analyse complex experiments involving multiple treatment conditions and block...

The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagen...

MOTIVATION: Accurate alignment of high-throughput RNA-seq data is a challenging and yet unsolved problem because of the non-contiguous transcript structure, relatively short read lengths and constantly increasing through...