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Objective: This study was aimed at the formation and evaluation of the mucoadhesive gastro-retentive tablet of domperidone to overcome the drawbacks related to the oral administration of drugs. These gastro retentive for...

Objective: Lidocaine needs to be administered frequently as it has poor oral bioavailability and it lacks prolong duration of action thus the study was aimed at to devise, develop, and analyze a matrix system transdermal...

Aim and Objective: The study aimed to manufacture Bucco-adhesive tablets of Risperidone and characterize the effectiveness of the drug by incorporating it into the mucoadhesive drug delivery system. The sustained release...

Objective: Development & Optimization of Ofloxacin Floating tablets to enhance gastric retention time. Sustained release effect of formulation will reduce the dosing frequency for UTIs and prolonged local effect will ben...

Cefuroxime axetil (CA) immediate release (IR) tablets were developed and optimized by direct compression method. Ten formulations were designed and optimized using central composite design with two main variables, microc...

The aim of this study was to formulate gliclazide loaded controlled release microspheres. Microspheres were prepared by quasi emulsion solvent diffusion technique using eudragit RLPO, eudragit RSPO and with their various...

The prolonged residence of drug formulation in the nasal cavity is of utmost importance for intranasal drug delivery. The objective of the present investigation was to develop a mucoadhesive in situ gel with reduced nasa...

The study aims to investigate a transdermal hydrogel formulation containing curcumin, which would attenuate the low bioavailability associated with oral administration of the drug. Carboxy polymethylene was used to devel...

The purpose of this study was to improve the meloxicam dissolution rate through its formulation into liquisolid compacts and then to evaluate the in vitro and in vivo performance of the prepared liquisolid compacts. Di...

The purpose of this study was to design a novel vaginal delivery system composed of metronidazole microspheres dispersed within a bioadhesive gel. Microspheres were prepared by solvent evaporation method using Eudragit...

A new reversible thermosensitive drug delivery system was designed and prepared by using chitosan and glycerophosphate with or without poly (ethylene glycol) and used as an a carrier for the Miconazole nitrate, an antifu...

Lipid-based nanocarriers were prepared by hot solvent diffusion technique. Tristearin (TS) and/or castor oil were employed as oily phase, and Lutrol F68® or Solutol HS15® and lecithin were employed as surfactant and co...

Materie / parole chiave: Ciencias Sociales; General

Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation, epithelial barrier disruption, and immune dysregulation. Cannabidiol (CBD), a non-psychoactive ph...

The increasing complexity of pharmaceutical management in pharmacies demands efficient systems to streamline drug classification and inventory control. As pharmacies handle a diverse range of formulations, including tabl...

Trichinellosis is a zoonotic disease affecting people all over the world, for which there is no speedy and reliable treatment. Albendazole (ABZ), an inexpensive benzimidazole used in oral chemotherapy against helminthic...

Multiproduct pipelines permit to transport large volumes of a wide range of refined petroleum products from major supply sources to distribution centers near market areas. Batches of refined products and grades are pumpe...

The aim of the present study was to evaluate the influence of the incorporation of caffeine as a model active ingredient on the quality attributes of a bioadhesive emulgel formulation previously optimized by Quality by D...

ABSTRACT A simple, rapid and sensitive spectrophotometric method for the determination of noradrenaline was developed. The method is based on the proton transfer reaction with alizarin red sulphonate (ARS) in aqueous neu...

ABSTRACT A simple, rapid and sensitive spectrophotometric method for the determination of phenylephrine hydrochloride was developed. The method is based on the proton transfer reaction with alizarin red sulphonate in aqu...

الملص ABSTRACT A simple and rapid spectrophotometric method has been developed for the determination of antiviral drug (Ganciclovir) in a bulk sample and in its dosage forms. The method depends on the ion-pair form...

After the ruling of the Constitutional Court (MK), Ministry of Home Affairs (MoHA) and the Provincial Government can no longer revoke the problematic Regional Regulation (Perda) via an executive review. This situation, w...

ABSTRACT Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require pa...

Usually, opinion formation models assume that individuals have an opinion about a given topic which can change due to interactions with others. However, individuals can have different opinions on different topics and the...