THYROID DISEASE : ENDOCRINOLOGY, SURGERY, NUCLEAR MEDICINE, AND RADIOTHERAPY
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Materie / parole chiave: RAVEN PRESS; 616.4404 T549t
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Cataloghi istituzionali, risorse elettroniche, riviste ad accesso aperto, collezioni disponibili e collegamenti per l’accesso accademico.
A Novel Missense Mutation in the SH2 Domain of the STAT5B Gene Results in a Transcriptionally Inactive STAT5b Associated with Severe IGF-I Deficiency, Immune Dysfunction, and Lack of Pulmonary Disease
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Context: Signal transducer and activator of transcription 5b (STAT5b) deficiency, first reported in a patient who carried a p.Ala630Pro missense mutation in the Src homology 2 (SH2) domain, results in a rare clinical con...
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Open AccessDietary iodide controls its own absorption through post-transcriptional regulation of the intestinal Na+/I- symporter
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Dietary I- absorption in the gastrointestinal tract is the first step in I- metabolism. Given that I- is an essential constituent of the thyroid hormones, its concentrating mechanism is of significant physiological impor...
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Open AccessEffect of the 3,5,3'-Triiodo-L-Thyronine on Zwitterionic and Anionic Membranes
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Vibrational spectroscopy is a powerful tool for understanding interactions between phospholipid membranes and molecules of biological relevance such as thyroid hormones. Particularly, 3,5,3´-triiodo L-thyronine (T3) has...
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Open AccessLevothyroxine Exhibits Inhibitory Effect towards UDP-Glucuronosyltransferase (UGT) 1A6-Mediated 4-Methylumbelliferone (4-MU) Glucuronidation
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Levothyroxine, a synthetic form of thyroid hormone, has been clinically used to treat thyroid hormone deficiency. UDP-glucuronosyltransferases (UGTs) are important phase II drug-metabolizing enzymes, and UGTs-inhibition ...
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Open AccessStrong Inhibition of UDP-Glucuronosyltransferase (UGT) 1A1 by Levothyroxine Indicates the Potential UGT-Inhibition Based Adverse Effect of Levothyroxine
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UDP-glucuronosyltransferase (UGT) 1A1, one of the most important UGT isoforms, can metabolize a variety of endogenous substances and xenobiotics. UGT1A1-catalyzed glucuronidation reaction plays a key role in many clinica...
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Open AccessFunción tiroidea y mortalidad en pacientes ancianos hospitalizados /
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Materie / parole chiave: Thyroid gland; Older people; Mortality; Thyroid gland diseases in old age; Thyroid gland function tests; Electronic books
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A combined model of BCVA, TRAb, and NLR predicts response to intravenous methylprednisolone in dysthyroid optic neuropathy
ISSN: 2296858X · Editore / fonte: Frontiers Media S.A.
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