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We discuss the following problem: given a random sample $\mathbf{X} = (X_1, X_2, \cdots, X_n)$ from an unknown probability distribution $F$, estimate the sampling distribution of some prespecified random variable $R(\mat...

X-ray diffraction analyses of five samples of pigments from a recently excavated mural at the archaeological site of Huaca Tacaynamo, a part of the Chan Chan archaeological complex, northern Peru, show that minerals rela...

Knaus, William A. MD; Draper, Elizabeth A. RN, MS; Wagner, Douglas P. PhD; Zimmerman, Jack E. MD Author Information

BACKGROUND: A short battery of physical performance tests was used to assess lower extremity function in more than 5,000 persons age 71 years and older in three communities. METHODS: Balance, gait, strength, and enduranc...

Abstract The introduction of AlphaFold 2 1 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in protein modelling and design 2–6 . Here we des...

BACKGROUND: Vitamin K antagonists are highly effective in preventing stroke in patients with atrial fibrillation but have several limitations. Apixaban is a novel oral direct factor Xa inhibitor that has been shown to re...

The ability of learning networks to generalize can be greatly enhanced by providing constraints from the task domain. This paper demonstrates how such constraints can be integrated into a backpropagation network through ...

Developments in genome-wide association studies and the increasing availability of summary genetic association data have made application of Mendelian randomization relatively straightforward. However, obtaining reliable...

BACKGROUND AND METHODS: National surveillance data show recent, marked reductions in morbidity and mortality associated with the acquired immunodeficiency syndrome (AIDS). To evaluate these declines, we analyzed data on ...

Materias / palabras clave: RNA; Sequence (biology); Molecule; Chemistry; In vitro; Riboswitch; Binding site; Computational biology; Population; Biology; Biochemistry; Non-coding RNA

BACKGROUND: The number of Mendelian randomization analyses including large numbers of genetic variants is rapidly increasing. This is due to the proliferation of genome-wide association studies, and the desire to obtain ...

In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic recommendations for the preclinical, mild cognitive impairment, and dementia stages of Alzheimer's disease. Scientific prog...

Raman spectra are reported from single crystals of graphite and other graphite materials. Single crystals of graphite show one single line at 1575 cm−1. For the other materials like stress-annealed pyrolitic graphite, ...

The Index of ADL was developed to study results of treatment and prognosis in the elderly and chronically ill. Grades of the Index summarize over-all performance in bathing, dressing, going to toilet, transferring, conti...

Saturation has attained widespread acceptance as a methodological principle in qualitative research. It is commonly taken to indicate that, on the basis of the data that have been collected or analysed hitherto, further ...

Abstract Principal component analysis (PCA) is a multivariate technique that analyzes a data table in which observations are described by several inter‐correlated quantitative dependent variables. Its goal is to extrac...

Fueron aisladas cuatro (4) lectinas presentes en las semillas de Artocarpus heterophyllus Lamk. ("jaca") mediante el uso de criterios de solubilidad y varias cromatografias de afinidad: goma de guar, quitina y agarosa-D-...

The present study describes some in vitro experiments with hydroalcoholic extract of leaves from Plectranthus amboinicus (Lour.) Spreng (Lamiaceae) in several Methicillin resistant Staphylococcus aureus (MRSA) strains in...

The hypoglycemic potential of crude ethanolic extract of leaves (CEE-Mn) of the Morus nigra L. (Moraceae) was evaluated in normoglycemic rats. CEE-Mn (200 and 400 mg/kg) and metformin (500 mg/kg) were tested on the glu...