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The aqueous solubility of drugs/drug candidates (Sw) is one of the crucial physicochemical parameters in drug discovery studies and any computational method to predict the solubility is highly in demand in the pharmaceut...

This work consists in the development of a computational model for the steam turbine currently operational in MoNiKa test facility plant, located in KIT-Campus Nord, Germany. Given that this corresponds to the first atte...

To research optimization possibilities in supercritical ORC processes for geothermal power production the Modular low-Temperature Circuit Karlsruhe (MoNiKa) was built at Campus North of the Karlsruhe Institute of Technol...

Summary The use of both linear and generalized linear mixed‐effects models ( LMM s and GLMM s) has become popular not only in social and medical sciences, but also in biological sciences, especially in the field of eco...

Simulation is the process of executing a model, that is a representation of a system with enough detail to describe it but not too excessive. This model has a set of entities an internal state, a set of input variable th...

One of the frequent questions by users of the mixed model function lmer of the lme4 package has been: How can I get p values for the F and t tests for objects returned by lmer? The lmerTest package extends the 'lmerMod' ...

The model selection literature has been generally poor at reflecting the deep foundations of the Akaike information criterion (AIC) and at making appropriate comparisons to the Bayesian information criterion (BIC). There...

Simultaneous inference is a common problem in many areas of application. If multiple null hypotheses are tested simultaneously, the probability of rejecting erroneously at least one of them increases beyond the pre-speci...

This paper proposes a model that predicts the complexity of Boolean functions with only XOR/XNOR min-terms using back propagation neural networks (BPNNs) applied to Binary Decision Diagrams (BDDs). The BPNN model (BPNNM)...

"In this work, a low-order model designed for glucose regulation in Type 1 Diabetes Mellitus (T1DM) is obtained from the UVA/Padova metabolic simulator. It captures not only the nonlinear behavior of the glucose-insul...

"The selection of a suitable master’s program has become an increasingly complex task due to the growing diversity of offerings and the lack of standardized comparable information across institutions. This thesis propo...

Tesis Energía y Ambiente (maestría) - Instituto Tecnológico de Buenos Aires - Karlsruher Institut für Technologie, Karlsruhe, 2020 In the present work a new empirical model for the phase-resolved body forces of an DB...

The present work deals with the comparison of in vitro dissolution profiles of fenofibrate liquisolid tablet formulations with those of marketed fenofibrate tablets, and the application of statistical methods to evaluate...

The distinct element method is a numerical model capable of describing the mechanical behaviour of assemblies of discs and spheres. The method is based on the use of an explicit numerical scheme in which the interaction ...

Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time ...

New protein parameters are reported for the all-atom empirical energy function in the CHARMM program. The parameter evaluation was based on a self-consistent approach designed to achieve a balance between the internal (b...

A rapid and accurate radiative transfer model (RRTM) for climate applications has been developed and the results extensively evaluated. The current version of RRTM calculates fluxes and cooling rates for the longwave spe...

Facing the different approaches to process activation and global termination detection on distributed systems, this paper performs a practical comparison between the mainly opposed centralized and distributed models. Fir...

The aim of present work was to compare the quality of different brands of gatifloxacin 200 mg tablets, collected from different retail pharmacies in the local market of Pakistan. Five different brands were characterized ...

Factor analysis, path analysis, structural equation modeling, and related multivariate statistical methods are based on maximum likelihood or generalized least squares estimation developed for covariance structure models...

(NOTE: Each chapter begins with an Introduction, and concludes with Exercises and References.) I. GETTING STARTED. 1. Aspects of Multivariate Analysis. Applications of Multivariate Techniques. The Organization of Data. D...

An extended period numerical integration of a baroclinic primitive equation model has been made for the simulation and the study of the dynamics of the atmosphere's general circulation. The solution corresponding to exte...

BACKGROUND: Gene set enrichment (GSE) analysis is a popular framework for condensing information from gene expression profiles into a pathway or signature summary. The strengths of this approach over single gene analysis...

Examines whether the positive association between social support and well-being is attributable more to an overall beneficial effect of support (main- or direct-effect model) or to a process of support protecting persons...