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Materias / palabras clave: Historia

This article presents the empirical evaluation of several simple metaheuristics applied to solve the Generalized Steiner Problem (GSP). This problem models the design of high-reliability communication networks, demanding...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAutomatic Recording Apparatus for Use in Chromatography of Amino AcidsD. H. Spackman, W. H. Stein, and Stanford. MooreCite this: Anal. Chem. 1958, 30, 7, 1190–1206Publication...

Singular integrals are among the most interesting and important objects of study in analysis, one of the three main branches of mathematics. They deal with real and complex numbers and their functions. In this book, Prin...

This paper follows the rational political budget cycle approach, ,extending it in two directions. First, it considers an open economy, to formalize the implications of political budget cycles for nominal exchange rates. ...

This paper describes various components of the macromolecular crystallographic refinement program REFMAC5, which is distributed as part of the CCP4 suite. REFMAC5 utilizes different likelihood functions depending on the ...

ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40-60-fold faster search and optimized model utiliz...

OBJECTIVES: This study attempts to develop a comprehensive set of comorbidity measures for use with large administrative inpatient datasets. METHODS: The study involved clinical and empirical review of comorbidity measur...

Materias / palabras clave: Medicine; Diabetes mellitus; Logistic regression; Population; Demography; Environmental health; Global health; Developing country; Public health; Economic growth; Economics; Internal medicine

BACKGROUND: Nivolumab, a fully human IgG4 programmed death 1 (PD-1) immune-checkpoint-inhibitor antibody, disrupts PD-1-mediated signaling and may restore antitumor immunity. METHODS: In this randomized, open-label, inte...

This study examines the relationship between use of Facebook, a popular online social network site, and the formation and maintenance of social capital. In addition to assessing bonding and bridging social capital, we ex...

The study was performed to compare the bioavailability of two hydroxyzine hydrochloride 25 mg tablet formulation in 16 volunteers of both sexes. The study was conducted open with randomized two period crossover design ...