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We describe a new computer program, SnpEff, for rapidly categorizing the effects of variants in genome sequences. Once a genome is sequenced, SnpEff annotates variants based on their genomic locations and predicts coding...

As firms move toward a more disciplined approach to e-business strategic planning, managers are seeking metrics that will help them analyze the success of their e-business investments. Likewise, researchers require metri...

From headwaters to mouth, the physical variables within a river system present a continuous gradient of physical conditions. This gradient should elicit a series of responses within the constituent populations resulting ...