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Xenopus laevis oocytes were injected with [14C] phe-tRNA and the fate of the aminoacyl moiety was studied. The radioactive phenylalanine is gradually hydrolized off the tRNA once inside the cell. The rate of deacylation ...

A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+. The compounds combine an 8-coordinate tetracarboxylate chelating site with stil...

Materias / palabras clave: Midpoint; Globular protein; Sequence (biology); Protein structure; Chemistry; Amino acid; Crystallography; Peptide sequence; Amino acid residue; Biophysics; Biochemistry; Biology

Materias / palabras clave: Biology; DNA; DNA damage; DNA repair; Molecular biology; Incubation; Irradiation; Cell; Homogeneous; Gel electrophoresis; Biophysics; Cell biology

Materias / palabras clave: Superhelix; Histone octamer; Nucleosome; Histone H1; Histone; Histone code; Biophysics; Histone H2A; Chemistry; DNA; Crystallography; Biology

Materias / palabras clave: Lipid raft; Membrane; Sphingolipid; Cell biology; Cell membrane; Signal transduction; Cell; Cell signaling; Raft; Biophysics; Chemistry; Biology

We introduce a method for optically imaging intracellular proteins at nanometer spatial resolution. Numerous sparse subsets of photoactivatable fluorescent protein molecules were activated, localized (to approximately 2 ...

Materias / palabras clave: Patch clamp; Current (fluid); Membrane; Resolution (logic); Current clamp; Materials science; Biophysics; Chemistry; Computer science; Biology; Electrophysiology; Neuroscience

The physiological and molecular mechanisms of tolerance to osmotic and ionic components of salinity stress are reviewed at the cellular, organ, and whole-plant level. Plant growth responds to salinity in two phases: a ra...

Materias / palabras clave: Electron microscope; Cryo-electron microscopy; Microscopy; Anisotropy; Materials science; Motion (physics); Optics; Electron; Biophysics; Physics; Nanotechnology; Nuclear magnetic resonance

Materias / palabras clave: Endothelium-derived relaxing factor; Bradykinin; Nitric oxide; Chemistry; Biological activity; Superoxide; Endothelium; Biophysics; Superoxide dismutase; Biochemistry; In vitro; Pharmacology

Materias / palabras clave: Allosteric regulation; Chemistry; Kinetics; Protein subunit; Enzyme; Enzyme kinetics; Biophysics; Monomer; Lactate dehydrogenase; Biochemistry; Stereochemistry; Active site

Materias / palabras clave: Biology; Reactive oxygen species; Signal transduction; Oxidative stress; Abiotic stress; Abiotic component; Cell biology; Cellular metabolism; Programmed cell death; Cell signaling; Mutant; Transduction (biophysics)

Materias / palabras clave: Transmembrane protein; Signal peptide; Computational biology; Protein Sorting Signals; SIGNAL (programming language); Cell biology; Chemistry; Biology; Biophysics; Computer science; Biochemistry; Peptide sequence

Aqueous solutions of lead salts (1, 2) and saturated

A fluid mosaic model is presented for the gross organization and structure of the proteins and lipids of biological membranes. The model is consistent with the restrictions imposed by thermodynamics. In this model, the p...

Materias / palabras clave: Biofilm; Extracellular polymeric substance; Extracellular matrix; Matrix (chemical analysis); Bacteria; Nucleic acid; Adhesion; Polysaccharide; Biology; Microbiology; Polymer; Biophysics

Materias / palabras clave: Capsaicin; Chemistry; Ion channel; Receptor; Transient receptor potential channel; TRPV1; Pharmacology; Biophysics; Medicine; Biology; Biochemistry

Materias / palabras clave: Acetylcholine; Muscarinic acetylcholine receptor; Thoracic aorta; Vasodilation; Aorta; Contraction (grammar); Chemistry; Anatomy; Vascular smooth muscle; Relaxation (psychology); Blood vessel; Biophysics

Materias / palabras clave: Chemistry; Autoxidation; Chloroplast; Lipid peroxidation; Photochemistry; Malondialdehyde; Oxygen; Chlorophyll; Chlorophyll a; Light intensity; Biochemistry; Nuclear chemistry

Materias / palabras clave: Disulfide bond; Chemistry; Heme; Biochemistry; Enzyme