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In the past, instruction fetch speeds have been improved by using cache schemes that capture the actual program flow. In this paper, we elaborate on the architecture and operation of an instruction cache named Variable-S...

Immune checkpoint inhibition represents a major recent breakthrough in the treatment of malignant diseases including breast cancer. Blocking the programmed death receptor-1 (PD-1) and its ligand, PD-L1, has shown impress...

BACKGROUND: Somatic mutations have the potential to encode "non-self" immunogenic antigens. We hypothesized that tumors with a large number of somatic mutations due to mismatch-repair defects may be susceptible to immune...

The use of some multiple-sequence alignments in phylogenetic analysis, particularly those that are not very well conserved, requires the elimination of poorly aligned positions and divergent regions, since they may not b...

We propose a novel image denoising strategy based on an enhanced sparse representation in transform domain. The enhancement of the sparsity is achieved by grouping similar 2-D image fragments (e.g., blocks) into 3-D data...

Chapter 1. Research Strategies and the Control of Nuisance Variables Chapter 2. Experimental Designs: an Overview Chapter 3. Fundamental Assumptions in Analysis of Variance Chapter 4. Completely Randomized Design Chapter...

A low-density parity-check code is a code specified by a parity-check matrix with the following properties: each column contains a small fixed number j \geq 3 of l's and each row contains a small fixed number k > j of...

The National High Blood Pressure Education Program presents the complete Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Like its predecessors, t...

"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure" provides a new guideline for hypertension prevention and management. The following are the k...