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The object of the present study was to investigate the anticancer properties of total alkaloids from Solanum lyratum Thunb (SLT-A), including the inhibitory effect of SLT-A on HeLa cells and the apoptosis-inducing capa...

Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated state. We show that four factors (OCT4, SOX2, NANOG, and LIN28) are suffic...

Human mesenchymal stem cells are thought to be multipotent cells, which are present in adult marrow, that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal ti...

Ganoderic acid Mk (GA-Mk), a triterpenoid acid, was isolated from the mycelia of Ganoderma lucidum, and no biological activity of GA-Mk has ever been reported. In this work, we investigated the effect of GA-Mk on the cel...

The aim of this study was to investigate the anticancer properties of crude flavonoids from Carya cathayensis Sargent bark (CCS-F), including the inhibitory effect of CCS-F on HeLa cells and the apoptosis-inducing capaci...

Breast cancer is the most common malignancy in United States women, accounting for >40,000 deaths each year. These breast tumors are comprised of phenotypically diverse populations of breast cancer cells. Using a model i...

Infiltrating stromal and immune cells form the major fraction of normal cells in tumour tissue and not only perturb the tumour signal in molecular studies but also have an important role in cancer biology. Here we descri...