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"Chemical processes simulation is an important instrument for the design, optimization and control of industrial plants. Simulation cases can be accomplished with relatively low costs and the absence of risks for the ope...

We have developed three computer programs for comparisons of protein and DNA sequences. They can be used to search sequence data bases, evaluate similarity scores, and identify periodic structures based on local sequence...

The present work deals with the comparison of in vitro dissolution profiles of fenofibrate liquisolid tablet formulations with those of marketed fenofibrate tablets, and the application of statistical methods to evaluate...

How can the variability present among different genomes, diverse regions within the same genome, among or within species be characterized and quantified? What factors influence this variability? Research of our group is ...

An ultraviolet (UV) spectrophotometric method was developed for the analysis of telithromycin, member of the ketolides, in drug substance and coated tablets. The method validation yielded good results, such as the range,...

Benjamini and Hochberg suggest that the false discovery rate may be the appropriate error rate to control in many applied multiple testing problems. A simple procedure was given there as an FDR controlling procedure for ...

Alpha-synuclein (SNCA) oligomers have been reported to inhibit autophagy. Aminochrome-induced SNCA oligomers are neurotoxic, but the flavoenzyme DT-diaphorase prevents both their formation and their neurotoxicity. Howeve...

Este informe describe los resultados de un estudio in vitro en el que fueron evaluados comprimidos de nevirapina (200 mg) de diferentes laboratorios brasileros. El producto roiginal fue la refencia, en comparación con c...

This research presents a fingerprint image processing algorithm for personal automatic identification, which has been in development since 1998. It is principally based on the comparison of the fingerprint's biometric pa...

Solid dispersions (SDs) of poorly water soluble diacerein were prepared with polyvinylpyrrolidone K30 at drug to polymer ratios of 1:1, 1:3 and 1:5 w/w utilizing kneading technique. Physical mixture (PM) was prepared at ...

Decisions involve many intangibles that need to be traded off. To do that, they have to be measured along side tangibles whose measurements must also be evaluated as to, how well, they serve the objectives of the decisio...