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The present investigation aims at feasibility assessment of ethyl cellulose (EC) and polyvinylpyrrolidone (PVP) based ondansetron hydrochloride matrix type transdermal systems. The effects of polymeric concentration, its...

Niosomes have been reported as a possible approach to improve the low skin penetration and bioavailability characteristics shown by conventional topical vehicle for Baclofen (centrally acting skeletal muscle relaxant)....

This work evaluated the influence of B-cyclodextrin (B-CD) on Eudragit® FS 30 D (FS) free film-forming capacity in the following blends: 90:10 and 95:5 (FS: B-CD) as material for potential application in colonic drug de...

Nanoemulsions are special emulsions that consist in a very small drop with sizes between 20 to 500 nm. When they are intended for topical application, the main problem of nanoemulsions is their low viscosity, which is re...

Rapid precorneal elimination of drug is a major limitation of conventional ophthalmic formulations. An ion activated in situ gel forming systems of an antibacterial agent moxifloxacin hydrochloride for instillation as dr...

Polymeric and lipid nanocapsules suspensions of the natural compound curcumin were prepared in order to overcome limitations associated with its clinical applications, such as poor aqueous solubility and susceptibility t...

Bilayer vesicles, such as liposomes and niosomes, are widely known as efficient delivery systems for drugs. Spherical vesicles consisting of amphipatic non-ionic surfactants named niosomes are arranged in one or more con...

Transdermal drug delivery systems of venlafaxine hydrochloride were prepared by using combination of hydrophilic (HPMC E15) and hydrophobic (ERS100 and ERL 100) polymers in 1:5, 2:4, 3:3, 4:2, 5:1 ratios by solvent casti...

Targeted delivery systems for treatment of Inflammatory bowel disease (IBD) are designed to increase local tissue concentrations of anti-inflammatory drugs from lower doses compared with systemic administration The objec...

The use of two alternative vegetable oils (grape seed oil and almond kernel oil) to prepare nanoparticulated delivery systems (nanocapsules and nanoemulsions) for active substances was evaluated. They were prepared by in...

This paper describes how to design low-cost reliable computing software for various application systems, by incorporating a single-version fault tolerant scheme along with run-time signature-based control-flow checking. ...

Providing Quality of Service (QoS) in Video on Demand systems (VoD) is a challenging problem. In this paper, we analyse the fault tolerance on a P2P multicast delivery scheme, called Patch Collaboration Manager / Multica...

The aim of the present study was to prepare, characterize and in-vitro evaluation of a Winsor-IV type microemulsion based drug delivery system incorporating celecoxib as BCS class-II model drug. Attempts were made to pre...