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Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes, express high levels of telomerase activity, and express cell surface markers that characterize primate embryonic stem cells but ...

We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio. We define seven broad periods of embryogenesis--the zygote, cleavage, blastula, gastrula, segmentation, pharyngula...

The process of programmed cell death, or apoptosis, is generally characterized by distinct morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is considered a vital component of various p...

Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated state. We show that four factors (OCT4, SOX2, NANOG, and LIN28) are suffic...

We have designed a system for targeted gene expression that allows the selective activation of any cloned gene in a wide variety of tissue- and cell-specific patterns. The gene encoding the yeast transcriptional activato...

Las translocaciones robertsonianas son las translocaciones más frecuentes en el ganado bovino. La primera translocación robertsoniana descripta en el Ganado bovino fue la 1/29. Al igual que otras fusiones céntricas es...

Los estudios en biotecnología canina están menos desarrollados que en otras especies. Las gametas y la reproducción canina en general tienen características únicas comparadas con las de otros mamíferos lo que hace ...

In situ hybridization (ISH) method allows to reveal specific genes expression, identify specific cell types and detect areas or tissues, displaying differential gene expression. This work describes a standardized procedu...