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The goal of this Thesis is reducing the global penalty associated to branch mispredictions, in terms of both performance degradation and energy consumption, through the use of confidence estimation. The reduction of this...

In the past, instruction fetch speeds have been improved by using cache schemes that capture the actual program flow. In this paper, we elaborate on the architecture and operation of an instruction cache named Variable-S...

The improvements in the crystal structure refinement program SHELXL have been closely coupled with the development and increasing importance of the CIF (Crystallographic Information Framework) format for validating and a...

The approach described in this paper represents a substantive departure from the conventional quantitative techniques of system analysis. It has three main distinguishing features: 1) use of so-called ``linguistic'' vari...

Motivation: Quality control and preprocessing of FASTQ files are essential to providing clean data for downstream analysis. Traditionally, a different tool is used for each operation, such as quality control, adapter tri...