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O principal objetivo deste trabalho foi desenvolver e caracterizar formulações de nanopartículas contendo dexametasona e avaliar a atividade antiinflamatória em ratos. As nanopartículas foram preparadas pelo método...

In the present study, we sought to systemically evaluate the biodistribution and the tumor-accumulation of N-succinyl-chitosan nanoparticles (Suc-Chi-NPs, 200 nm in diameter) in model tumor-bearing mice and also the bind...

Nanoparticles are widely utilized to overcome drugs insolubility problems and sustain release improving the bioavailability. Zinc phthalocyanine, a hydrophobic photosensitizer with solubility problems, was loaded in PLA ...

Benzocaine (BZC) is an ester-type local anesthetic used mainly in topical, dermal and mucosal formulations. The present work consists of the development and validation of analytical methodology for evaluation of benzocai...

The use of two alternative vegetable oils (grape seed oil and almond kernel oil) to prepare nanoparticulated delivery systems (nanocapsules and nanoemulsions) for active substances was evaluated. They were prepared by in...

The aim of the present study was to evaluate the in vitro toxicity of two multi wall carbon nanotubes (MWCNT) on human hepatocytes (Hep G 32 cell lines). The toxic effects of carbon nanoparticles were analyzed after 48 h...

Optical detection and spectroscopy of single molecules and single nanoparticles have been achieved at room temperature with the use of surface-enhanced Raman scattering. Individual silver colloidal nanoparticles were scr...

The optical properties of metal nanoparticles have long been of interest in physical chemistry, starting with Faraday's investigations of colloidal gold in the middle 1800s. More recently, new lithographic techniques as ...

Cymbopogon citratus essential oil (CCEO) is widely used in food, cosmetics and pharmaceutical fields. The aim of this study was to compare two different methods of encapsulating CCEO. The o/w emulsion method was employed...