Buscar recursos académicos

BACKGROUND: Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions. Nevertheless, the majority of available protein-protei...

Proteins from silver-stained gels can be digested enzymatically and the resulting peptide analyzed and sequenced by mass spectrometry. Standard proteins yield the same peptide maps when extracted from Coomassie- and silv...

Materias / palabras clave: Stable isotope labeling by amino acids in cell culture; Proteome; Peptide; Mass spectrometry; Label-free quantification; Chemistry; Quantitative proteomics; Proteomics; Computational biology; Fragmentation (computing); C...

This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation. This addresses the challenge of finding organism...

Materias / palabras clave: Computer science; Plug-in; Workflow; Software; Usability; Proteomics; Python (programming language); Data science; Data mining; Human–computer interaction; Programming language; Biology

Resolving the molecular details of proteome variation in the different tissues and organs of the human body will greatly increase our knowledge of human biology and disease. Here, we present a map of the human tissue pro...

Materias / palabras clave: Proteome; Chromatography; Sodium dodecyl sulfate; Sample preparation; Mass spectrometry; Chemistry; Proteomics; Digestion (alchemy); Filter paper; Organelle; Solubilization; Elution

Part I: Molecular Biology of Cancer Molecular Methods in Oncology Section 1. Amplification Techniques Section 2. RNA Interference Section 3. cDNA arrays Section 4. Tissue arrays Section 5. Cytogenetics Section 6. Bioinfo...

The 11th edition of the Manual of Clinical Microbiology continues to set the standard for state-of-the-science laboratory practices as the most authoritative reference in the field of clinical microbiology. This new edit...

Much of the complexity within cells arises from functional and regulatory interactions among proteins. The core of these interactions is increasingly known, but novel interactions continue to be discovered, and the infor...

Increasing quantitative data generated from transcriptomics and proteomics require integrative strategies for analysis. Here, we present an R package, clusterProfiler that automates the process of biological-term classif...