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Materias / palabras clave: Proteome; Chromatography; Sodium dodecyl sulfate; Sample preparation; Mass spectrometry; Chemistry; Proteomics; Digestion (alchemy); Filter paper; Organelle; Solubilization; Elution

"Chemical modification of bacterial cellulose (BC) through carboxymethylation was carried out to prepare a low-cost highly stable lead adsorbent material (CMBC). Aiming to maximize its adsorption capacity, the effect of ...

"A rapid and sensitive analytical method for the trace determination of aflatoxin M1 in domestic waters was developed using chitosan as a sorbent and HPLC with fluorescence detection (HPLC-FLD). Computational simulations...

The purpose of the present study was to prepare spherical agglomerates (SA) of piroxicam by solvent change method. Crystallization medium used for spherical agglomerates of piroxicam consisted of DMF:water and chloroform...

Cabergoline (CAB) is a synthetic ergoline dopamine agonist with high affinity to D2 receptors, thus used for the treatment of Parkinson's patients and hyperprolactinemia disorders. In this study, simple, fast, reliable a...

The objective of this paper was to develop a high performance liquid chromatography with diode array detection both for chromatographic fingerprint and simultaneous determination of twelve analytes of Shuang-Huang-Lian (...

A simple and sensitive LC-ESI-MS method for determination of norvancomycin in plasma was developed and validated over the concentration range of 20-2,000 ng/mL. After addition of vancomycin as internal standard (IS), p...

A sensitive and selective liquid chromatography tandem mass spectrometry (LC-MS/MS) method for determination of diphenhydramine hydrochloride in rabbit plasma was developed and validated. After addition of triazolam as i...

A sensitive and selective liquid chromatography-mass spectrometry (LC–MS) method for determination of esomeprazole in rabbit plasma was developed and validated. After addition of midazolam as internal standard (IS), pr...

A sensitive and selective liquid chromatography-mass spectrometry (LC-MS) method for determination of ibudilast in rabbit plasma was developed and validated. After addition of estazolam as internal standard (IS), protein...

Nowadays there are no official in vitro methods to determine TiO2, ZnO or other inorganic elements in sunscreen cosmetics. The objective of this work is to determine the concentration of several inorganic elements in sun...

A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of ketamine in rabbit plasma using one-step protein precipitation was developed and validated. After additi...

A sensitive and selective liquid chromatography tandem mass spectrometry (LC–MS/MS) method for determination of meropenem in rabbit plasma was developed. After addition of triazolam as internal standard (IS), protein p...

A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of ramosetron in rat plasma using one-step protein precipitation was developed and validated. After additio...

A sensitive and selective liquid chromatography/electrospray mass spectrometry (LC-ESIMS) method for determination of tetramethylpyrazine in rat plasma was developed. After addition of phenacetin as internal standard, ...

A sensitive and selective liquid chromatography-tandem mass spectrometry method (LC-MS/MS) for the determination of tolbutamide in rabbit plasma was developed and validated over the concentration range of 4-1000 ng mL-...

A sensitive and selective liquid chromatography/electrospray mass spectrometry (LC-ESIMS) method for determination of troxerutin in rabbit plasma was developed. After addition of paeoniflorin as internal standard (IS), p...

A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of dapoxetine in rat plasma using one-step protein precipitation was developed and validated. After additio...

A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of torsemide in rabbit plasma using one-step protein precipitation was developed and validated. After addit...

This paper describes a rapid (2.0 min) and sensitive (LLOQ 5 ng/mL) analytical method for the quantitation of hydrochlorothiazide (HCTZ) in human plasma. The method is based on High-performance Liquid chromatography-tand...

To develop a high performance liquid chromatography method for the simultaneous determination of cortisone and cortisol in rat serum and apply it for pharmacokinetics. After addition of pirfenidone as internal standard (...

Proteins from silver-stained gels can be digested enzymatically and the resulting peptide analyzed and sequenced by mass spectrometry. Standard proteins yield the same peptide maps when extracted from Coomassie- and silv...

El uso extenso de agentes antineoplásicos en quimioterapia se considera un riesgo relevante para el personal implicado en la preparación y la administración de estos medicamentos. En este estudio la ciclofosfamida, un...

PURPOSE: Standards for reporting exist for many types of quantitative research, but currently none exist for the broad spectrum of qualitative research. The purpose of the present study was to formulate and define standa...