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Cylin dependent kinases (CDKs) have emerged as novel mechanistic target due to their direct involvement in underlying genetic changes during the cancerous state. In order to identify the essential physiochemical paramete...

Non-irritant, non-comedogenic and non-polar emollients were pre-selected for determinations of relative dielectric permittivity and solubility of benzoyl peroxide (BP). Those solvents capable of solubilizing BP in concen...

Metformin hydrochloride (MH), an important drug in the treatment of type II diabetes mellitus, requires multiple administration in 500-1500 mg doses/day. Sustained release gastro retentive multiparticulates of MH were pr...

The aim of present work was to compare the quality of different brands of gatifloxacin 200 mg tablets, collected from different retail pharmacies in the local market of Pakistan. Five different brands were characterized ...

The ternary solid dispersion systems of poorly water soluble olmesartan medoxomil (OLM) were prepared by conventional kneading method in order to improve its physicochemical performance. A 32 full factorial design approa...

E-mail texts are hard to process due to their short length. In this article, the use of a diffuse neural network that is capable of identifying the most relevant terms in a set of e-mails is proposed. The associations be...

The objective of the present investigation was to investigate the effects of selected drugs (captopril and celecoxib) properties on different parameters drug entrapment, in vitro drug release, release pattern, in vitro d...

This article investigates enhancement of the dissolution profile of gliclazide, an antidiabetic drug, using the combination of solid dispersions and melt adsorption techniques. Poloxamer and PEG 6000 were utilized as hyd...

To select the suitable concentration level of controlled release polymer for the formulation of predefined extended release formulation based on the solubility behaviour of active substance, we have formulated and evalua...

Microspheres were prepared using the emulsion/solvent evaporation method with the aim of obtaining diclofenac sodium (DFS) prolonged release dosage forms. The effects of the drug:polymer ratio and addition of Pluronic F6...

The aim of the study was to formulate and evaluate controlled release microspheres. Ciprofloxacin HCl, belonging to the class of fluroquinolones, was chosen as the model drug. The drugloaded microspheres were prepared wi...

The present study involves preparation and characterization of floating multiparticulate microcapsules with Simvastatin as model drug for prolongation of gastric residence time. The main objective is to improve solubilit...

In this paper, we present a new reversible data hiding scheme that utilizes the wavelet transform and better exploits the large wavelet coefficient variance to achieve high capacity and imperceptible embedding. Our schem...

To develop a high performance liquid chromatography method for the simultaneous determination of cortisone and cortisol in rat serum and apply it for pharmacokinetics. After addition of pirfenidone as internal standard (...

In the present work, orodispersible tablets of atomoxetine HCl were designed by preparing tasteless complexes of atomoxetine HCl with weak cation ion exchange resins (Kyron T 134). The ion exchange complex were prepared ...

The prescription of antibiotics worldwide remains large, especially in children. The lack of accurate diagnoses leads to overuse of these drugs, increasing bacterial resistance. A large number of studies have shown that ...

There are considerable number of approaches to policy specification both for security management and policy driven network management purposes as reported in [20]. This specification sort security policies into two basic...

A simple isocratic method for quantification of hydroxyzine dihydrochloride by HPLC with UV detection at 232 nm in syrup has been developed and validated. Separation was achieved on a C18 column (250 x 4.6 mm, 5 μm) mai...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

In this paper, a trajectory tracking control for a nonholonomic mobile robot subjected to uncertainties and disturbances in the kinematic model is proposed. An adaptive variable structure controller based on the sliding ...

Several species of the Polygonum genera are collectively known in Brazil under the name "erva-de-bicho". In tradicional medicine, these species often mistaken for each other and are probably used for the same therapeutic...

D-002, a mixture of six beeswax alcohols, with gastroprotective and anti-inflammatory effects, was compared with naproxen, aspirin and their combined therapy in rats with cotton pellet granuloma. After pellet implantatio...

Manilkara subsericea (Mart.) Dubard (Sapotaceae) is popularly known in Brazil as "guracica". The species from the genus Manilkara have been studied and several substances were found, including triterpenes. In the present...

The methanol extract of the whole plant of Eclipta prostrata and one of its isolated compounds, eclalbasaponin II were administered to alloxan-induced diabetic rats for 28 and 7 consecutive days, respectively. During the...