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Nowadays,it's well-known that Small and Medium Enterprises (SMEs) generate important contributions to the software industry. Their particular characteristics constitute a challenge to decision makers when selecting techn...

"The emergence of mosquitoes that can avoid indoor-deployed interventions, such as treated bed nets and indoor residual spraying, threatens the mainstay of malaria control in Zambia. Furthermore, the requirement for high...

El artículo está destinado a subrayar el proyecto ARISTARCUS, un conjunto de herramientas de trabajo para la investigación y la enseñanza en temas del área de mundo antiguo Griego y Latino y está disponible en el s...

Las analogías entre sistemas enconómicos y sistemas termodinámicos son a la vez obvias y engañosas. Aún si importantes nociones de la termodinámica no encuentran su contraparte en la economía, la transferencia del...

This research paper uses the terms "tools" to include the computer hardware, software, and connectivity put together under the title Information and Communication Technology (ICT). Authors of this research work considere...

CCP4mg is a project that aims to provide a general-purpose tool for structural biologists, providing tools for X-ray structure solution, structure comparison and analysis, and publication-quality graphics. The map-fittin...

Functional analysis of large gene lists, derived in most cases from emerging high-throughput genomic, proteomic and bioinformatics scanning approaches, is still a challenging and daunting task. The gene-annotation enrich...

The MEME Suite web server provides a unified portal for online discovery and analysis of sequence motifs representing features such as DNA binding sites and protein interaction domains. The popular MEME motif discovery a...

MOTIVATION: Fast and accurate quality control is essential for studies involving next-generation sequencing data. Whilst numerous tools exist to quantify QC metrics, there is no common approach to flexibly integrate thes...

"Various tools for program analysis, including run-time assertion checkers and static analyzers such as verification and test generation tools, require formal specifications of the programs being analyzed. Moreover, many...

"The amount of multidimensional data published on the semantic web (SW) is constantly increasing, due to initiatives such as Open Data and Open Government Data, among other ones. Models, languages, and tools, that allow ...

The resolution of optimization problems is of great interest nowadays and has encouraged the development of various information technology methods to attempt solving them. There are several problems related to Software E...

A valid Calderbank-Shor-Steane (CSS) error correction code requires two classical linear codes for the preparation of the initial state (codewords). This code allow to correct for certain errors caused by an unwanted int...

In the MDE (Model Driven Engineering) paradigm, models are thought to be the primary conductors in all software development aspects. A PIM (Platform Independent Model) is transformed into one or more PSMs (Platform Speci...

Agents repesent a new paradigm for developing software applications. In spite of the interest of this particular way of looking at problems, there is considerable discrepancy on exactly what is an agent and which are the...

UCSF ChimeraX is the next-generation interactive visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX brings (a) significant performance and gr...

BACKGROUND: There is no single generally accepted clinical definition of frailty. Previously developed tools to assess frailty that have been shown to be predictive of death or need for entry into an institutional facili...

Abstract The introduction of AlphaFold 2 1 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in protein modelling and design 2–6 . Here we des...

In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biologic...

Coot is a molecular-graphics application for model building and validation of biological macromolecules. The program displays electron-density maps and atomic models and allows model manipulations such as idealization, r...

Comparative protein modeling is increasingly gaining interest since it is of great assistance during the rational design of mutagenesis experiments. The availability of this method, and the resulting models, has however ...

The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia. EWGSOP included representatives from four particip...

MOTIVATION: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling ...

Motivation: Quality control and preprocessing of FASTQ files are essential to providing clean data for downstream analysis. Traditionally, a different tool is used for each operation, such as quality control, adapter tri...