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BACKGROUND: Traditional approaches to mechanical ventilation use tidal volumes of 10 to 15 ml per kilogram of body weight and may cause stretch-induced lung injury in patients with acute lung injury and the acute respira...

"Reverse triggering (RT) is a dyssynchrony defned by a respiratory muscle contraction following a passive mechanical insufation. It is potentially harmful for the lung and the diaphragm, but its detection is challenging...

This study evaluates whether reductions in airway pressure-time product (ΔPTPaw) during diaphragm neurostimulation-assisted ventilation can reliably quantify respiratory muscle effort. Using data from the STIMULUS trial...

"To evaluate the use of non-invasive variables for monitoring an open-lung approach (OLA) strategy in bariatric surgery. Twelve morbidly obese patients undergoing bariatric surgery received a baseline protective ventilat...

"Background: The prevalence of reverse triggering (RT) in the early phase of ARDS is unknown. Research question: During early ARDS, what is the proportion of patients affected by RT, what are its potential predictors, ...

"To evaluate a novel physiological approach for setting the tidal volume in mechanical ventilation according to inspiratory capacity, and to determine if it results in an appropriate mechanical and gas exchange measurem...

BACKGROUND: Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. METHODS...

BACKGROUND: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. METH...

Importance: There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19). Objective: To describe the clinical charac...

Materias / palabras clave: Medicine; ARDS; Pneumonia; Intensive care unit; Retrospective cohort study; Mechanical ventilation; Incidence (geometry); Intensive care; Severity of illness; APACHE II; Internal medicine; Pediatrics

The acute respiratory distress syndrome (ARDS) was defined in 1994 by the American-European Consensus Conference (AECC); since then, issues regarding the reliability and validity of this definition have emerged. Using a ...

Importance: In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patien...

BACKGROUND: Hyperglycemia and insulin resistance are common in critically ill patients, even if they have not previously had diabetes. Whether the normalization of blood glucose levels with insulin therapy improves the p...