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Abstract Background Biallelic SPG7 mutations cause one of the most common forms of hereditary spastic paraplegia (HSP). Several reports have suggested that heterozygous SPG7 variants may also play a role in HSP, but also...

Lung transplantation (LTx) remains limited by high immunogenicity and chronic rejection, yet the application of donor-specific blood transfusion (DSBT) in LTx has not been fully investigated. We established a murine orth...

This systematic review, conducted under the COST Action CA20218 “Promoting Innovation of fermented foods” (PIMENTO), aimed to evaluate whether sourdough- and regular-bread fermentation improve iron bioavailability, a...

The development of anti-CD3 antibody-based T cell engager therapeutics has improved the treatment of various malignancies, yet the challenge of achieving tumor-specific targeting while minimizing on-target off-tumor effe...

Interleukin-10 (IL-10) is the most important anti-inflammatory cytokine at intestinal level, and its absence is involved in inflammatory bowel diseases. However, oral treatment with IL-10 is difficult because of its low ...

Abstract The ability of organisms to learn and remember is crucial for their survival. This cognitive ability spans a wide range of organisms, including both vertebrates and invertebrates, yet has remained little studied...

Abstract Background After‐hours or out‐of‐clinic crossmatches are often limited by the lack of access to specialized material and technical expertise. Hypothesis/Objectives The goal was to adapt a stall‐side cros...

Abstract This study compares dynamic stability between individuals with obesity and those of normal weight. Participants performed audiomotor synchronization tasks involving a metronome with sudden phase shifts, both whi...

Abstract This is the protocol for a Campbell systematic review. The review will address the following research questions: What is the evidence on the effects of adult mentoring programmes in reducing anti‐social, viole...

Abstract Background Semaglutide, a glucagon-like peptide-1 receptor agonist, and resmetirom, a thyroid hormone receptor-β agonist, are approved therapies for noncirrhotic metabolic dysfunction–associated steatohepatit...

Integrated silicon nanophotonics has rapidly established itself as intriguing research field, whose outlets impact numerous facets of daily life. Indeed, nanophotonics has propelled many advances in optoelectronics, info...

Category: Hindfoot, Ankle Arthritis Keywords: Wound Complications, Total Ankle Arthroplasty, Revision Ankle Arthroplasty Introduction/Purpose: Total ankle arthroplasty (TAA) preserves motion, while ankle arthrodesis (AF)...

Aims: This audit aimed to assess compliance with British Orthopaedic Association Standards for Trauma (BOAST) for paediatric forearm and wrist fractures across UK NHS hospitals and identify targets for improvement locall...

Photonic reservoir computing has been demonstrated to be able to solve various complex problems. Although training a reservoir computing system is much simpler compared to other neural network approaches, it still requir...