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Introduction: Ventilator Associated Pneumonia (VAP) is a common Healthcare Associated Infection (HAI) in mechanically ventilated patients, leading to increased morbidity, mortality, Intensive Care Unit (ICU) stays, and h...

Quinolines are well-established scaffolds in drug discovery and form the core of many FDA-approved medicines. Among their reduced analogues, hexahydroquinolines (HHQs) have gained increasing attention due to their struct...

Mentha suaveolens subsp. timija is an aromatic herb with a spearmint flavor that plays an important role in the treatment of a wide range of diseases. It has various biological activities, including serving as a natural ...

Ziye Liu,1 Meiyu Deng,2 Bu Wang,2 Jianhua Liu,2 Wei Zhang,3,* Jianqing Zhao2,* 1Department of Respiratory Medicine, The First School of Clinical Medicine, Hebei North University, Zhangjiakou, Hebei, Peopl...

Aims: To evaluate the inhibition effectiveness of enterocin CRL35 in combination with cell wall, membrane-acting antibiotics and muranolytic enzymes against the foodborne pathogen Listeria.Methods and Results: Synthetic ...

Cancer therapy and food preservation both face significant challenges related to stability, targeted delivery, safety, and efficiency of active compounds. Biopolymer-based nanoparticles, particularly those derived from c...

Acne vulgaris is a common inflammatory skin condition that affects up to 85% of adolescents and is primarily driven by Cutibacterium acnes (anaerobic bacteria, formerly Propionibacterium acnes). With the rise of antibiot...

Millions of microorganisms—including bacteria, viruses, fungi, archaea, and protists—reside on and within the human body, collectively forming the human microbiota. This complex and dynamic community plays a crucial ...

The use of edible films to release antimicrobial constituents in food packaging is a form of active packaging that contributes to extend the shelf-life of a product and provides microbial safety for consumers. A number o...

Enterococcus faecalis adalah bakteri yang paling banyak terdapat pada infeksi saluran akar yang telah dirawat endodontik. Chlorhexidine mempunyai daya anti bakteri spektrum luas dan telah digunakan dalam endodontik seb...

Abstract This study reports the sustainable green synthesis of magnesium oxide nanoparticles (MgONPs) using peel extracts from two avocado cultivars, Persea americana Mill. Hass and Fuerte, and demonstrates the strong in...

Background and objectives: Biofilms have a major medical significance as they decrease susceptibility to antimicrobial agents. The decreased susceptibility to microbial agents within a biofilm arises from multiple factor...

Abstract Curcumin, a natural polyphenol with multifaceted anticancer properties, faces significant clinical translation challenges due to poor solubility, rapid metabolism, and low bioavailability. Hydrogels, as biocompa...

ABSTRACT Background and Aims Septic abortion remains a major cause of maternal morbidity and mortality in low‐ and middle‐income countries. This study aimed to determine the prevalence, antibiotic susceptibility prof...

Abstract Background Antimicrobial resistance (AMR) represents a major global One Health challenge, with increasing recognition of the role of wildlife in the environmental circulation of resistant bacteria. Wild birds, p...

ESKAPE, including Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. pose a significant global health threat due to their extensive ...

Abstract Amphibians are enjoyable globally for their culinary value and are increasingly considered alternative protein sources. However, the skin of edible amphibians, especially giant salamanders, is often discarded wi...

Abstract 2-Mercapto benzimidazole derivatives are well-recognized for their diverse pharmacological activities, including anti-tubercular, antimicrobial, anti-ulcer, analgesic, and anticancer properties. Isoniazid, a fir...

Abstract Introduction Bone and joint infections (BJIs) are complex and difficult to eradicate, and have high relapse rates and limited oral treatment options. Tetracyclines combine favorable bone penetration, oral bioava...

Antimicrobial drugs are widely used in commercial ointments to treat different types of wounds.  Unwise use of antimicrobials in ointment formulations only deepens the problem of antimicrobial resistance. Some natural p...

Abstract Background Salvia fruticosa (Lamiaceae) is traditionally used to treat gastrointestinal (GIT) issues, stomach and abdominal pain, and ulcers. In this work, we aimed to extract essential oils (EOs) from the aeria...

Chlamydia psittaci is an obligate intracellular pathogen that poses a significant threat to both human and animal health. The current therapeutic strategies are limited by the emergence of potential drug resistance, unde...

Abstract Background Euphorbia milii is a flowering ornamental plant that plays an important role in folk medicine. It has a variety of therapeutic effects due to its high content of many active compounds. This research p...

Otitis media is a prevalent condition affecting individuals of all ages, often accompanied by symptoms such as ear pain, fluid accumulation, and possible hearing loss. Bacterial infections are among the leading causes, w...