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Abstract Background In Swaziland, as in many high HIV/TB burden settings, there is not information available regarding the household location of TB cases for identifying areas of increased TB incidence, limiting the deve...

Tuberculosis (TB) vaccine design relies on the selection of optimal antigens. However, evidence on candidate antigens is scattered across the literature and rarely linked to critical vaccine parameters, such as immune re...

Peritonitis is the most common and serious complication of continuous ambulatory peritoneal dialysis (CAPD). Nevertheless, tuberculosis peritonitis in uremic patients undergoing CAPD therapy occurs infrequently. A case o...

ObjectiveTo systematically evaluate the incidence of tuberculosis (TB) in cancer patients treated with immune checkpoint inhibitors (ICIs) and compare the risk of TB between ICI-treated and non-ICI-treated cancer patient...

Mixed infection refers to the presence of multiple Mycobacterium tuberculosis strains within one host, while heteroresistance denotes the coexistence of drug-susceptible and drug-resistant strains or genotypes. Mixed inf...

HIV coinfection and multidrug-resistant tuberculosis (MDR-TB) pose a major public health challenge in sub-Saharan Africa, where high HIV prevalence promotes tuberculosis progression and complicates its management. In peo...

IntroductionAsymptomatic individuals with negative Interferon-γ release assay (IGRA) and tuberculin skin test (TST) results are often labeled as tuberculosis-unexposed individuals. We hypothesize that flow cytometric (F...

Mycobacterium tuberculosis (M.tb.) infection leads to over 1.5 million deaths annually, despite widespread vaccination with BCG at birth. Causes for the ongoing tuberculosis endemic are complex and include the failure of...

Tuberculosis is a global public health challenge, disproportionately affecting adolescents in low-and middle-income countries. Malnutrition worsens immune function, delays recovery and increases the risk of treatment fai...

In Argentina, multidrug-resistant tuberculosis (MDR-TB) outbreaks emerged among hospitalized patients with AIDS in the early 1990s and thereafter disseminated to the immunocompetent community. Epidemiological, bacteriolo...

Background: Tuberculosis (TB) remains a global public health challenge, with Thailand identified as a high-burden country for TB and TB-HIV infections by WHO in 2021–2025. While the standard TB treatment regimen—incl...

Abstract Background Tuberculosis remains a major public health challenge in Somalia, where a fragile health system and reliance on private providers complicate care. Although Public-Private Partnerships are globally reco...

Background: Tuberculosis remains one of the primary infectious diseases in Bangladesh that affects both adults and children. Poor diagnostic criteria and insufficient reporting, especially of pulmonary tuberculosis (PTB)...

Background: Drug-resistant tuberculosis (DR-TB) is a major public health challenge in Sub-Saharan Africa (SSA), worsened by high HIV prevalence and limited healthcare infrastructure. Bedaquiline, a cornerstone DR-TB trea...

Abstract Background Tuberculosis (TB) remains a petrified condition with a huge economic and health impact on families and health systems in Ghana. Monitoring of TB programme performance indicators can provide reliable d...

We developed a new multiplexed-PCR assay to accurately classify Mycobacterium tuberculosis complex (MTC) isolates at the sublineage level by single nucleotide polymorphisms (SNPs). This method relies on 7 SNPs located in...

The results obtained in evaluating the efficiency of a Neuro-Fuzzy System NEFCLASS (Neuro-Fuzzy Classification) in image classification of cattle tuberculosis, based on its texture features extracted using the wavelet tr...

Introduction: Mental health issues are prevalent, yet their treatment remains inadequate. Tuberculosis presents substantial mental health challenges. Their co-occurrence is a frequent phenomenon. However, the integration...

Background: Abdominal tuberculosis (ATB) in children presents a diagnostic challenge due to its nonspecific clinical presentation and low microbiological yield. Imaging plays a crucial role in supporting diagnosis, parti...

Background: This study aims to evaluate the clinical value and safety of hand–drawn mapping for bronchoscopic navigation combined with radial probe endobronchial ultrasound (RP–EBUS) in the diagnosis of primary perip...

Recurrent tuberculosis (TB) accounts for 30% of the annual TB burden in Cape Town. To better understand mechanisms behind recurrences, we assessed the association between neighborhood factors and the cumulative number of...

Objectives: To describe the experiences of U.S. tuberculosis (TB) program officials participating in contact investigations after TB exposures on aircraft in order to 1) characterize barriers to participation and 2) bett...

Background: Ankylosing spondylitis (AS) frequently produces thoracic-cage deformities-kyphosis and rib fusion-that restrict chest expansion and impair ventilation, occasionally progressing to atelectasis or pulmonary fib...

Abstract Background Rifampicin-resistant tuberculosis (RR-TB) remains a major public health concern, particularly in African populations where undernutrition is common. Many participants with RR-TB initiate treatment wit...