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Inborn errors of immunity (IEI) are increasing in number, and prompt recognition and diagnosis remain a challenge for clinicians. Use of machine learning (ML) for clinical pattern recognition is promising but has been li...

Abstract Model instability remains a core challenge for data‐driven parameterizations, especially those developed with supervised algorithms, and rigorous methods to address it are lacking. Here, by integrating machine...

We study several simplified dark matter (DM) models and their signatures at the LHC using neural networks. We focus on the usual monojet plus missing transverse energy channel, but to train the algorithms we organize the...

Abstract Background Bacterial diseases include any illness caused by bacteria. Bacteria are tiny microorganisms that can only be seen with a microscope. Other types of microorganisms include viruses, fungi, and some para...

BackgroundSarcopenia, an age-correlated decline in skeletal muscle mass and function, has been increasingly linked to ferroptosis, which is an iron-dependent form of regulated cell death driven by lipid peroxidation. Nev...

Nanophotonics inverse design is a rapidly expanding research field whose goal is to focus users on defining complex, high-level optical functionalities while leveraging machines to search for the required material and ge...

Tuberculosis (TB) continues to be one of the foremost public health issues in the world, and remains the second most salient communicable cause of death after COVID-19. In 2022, TB accounted for 10.6 million new infectio...

Abstract The Broad Learning System (BLS) provides an effective framework for nonlinear mapping, offering advantages over traditional deep neural networks through its expanded input node architecture. While BLS has demons...

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

Airport planning depends to a large extent on the levels of activity that are anticipated. To plan the facilities and infrastructures of an airport system and to be able to satisfy future needs, it is essential to predic...

Abstract Background Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder that is linked to cardiovascular, metabolic, and neurocognitive complications. However, its diagnosis relies on polysomnograp...

Abstract Background Lung adenocarcinoma (LUAD) is a predominant contributor to cancer‑related mortality globally. Lung‑associated fibroblasts (LAFs) are intricately linked to tumorigenesis and the tumor microenvironm...

A wall jet is a typical flow field encountered in various engineering fields, including the deviation tunnels, the bottom outlets of dams, and wastewater treatment. Appropriate prediction of wall jet characteristics is h...

This study seeks to enhance lead conversion for online professional education providers by using supervised machine learning algorithms for lead conversion targeting and lead scoring, including Logistic Regression, K-Nea...

BackgroundChronic hepatitis B (CHB) caused by the hepatitis B virus (HBV) remains a major global health burden. The immune-active (IA) phase, characterized by positive Hepatitis B surface antigens (HBsAg), elevated alani...

Abstract Background The role of extrachromosomal DNA (ecDNA)-related genes in osteosarcoma remains largely unexplored. The aim of this study is to investigate the association between ecDNA-related genes and prognosis and...

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder. The risk of frailty is significantly higher in patients with PD than in age-matched individuals without PD. This study aimed to...

Abstract The increase in vehicle ownership and urban population puts a strain on roads and increases traffic congestion within developed and developing nations. Congestion affects an individual’s time and increases an ...

Background Lupus nephritis (LN) is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), and the accurate classification of renal pathological subtypes is crucial for reducing mortality rates ...

Abstract Background Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy characterized by rapid progression and poor prognosis. This study integrates bioinformatics with experimental validation to cha...

BackgroundThe dengue virus (DENV) can cause various clinical syndromes and organ damage, known as dengue fever, with the probability of developing severe dengue. However, the underlying mechanisms of host response agains...

Even with the introduction of additional security features, the progression toward 6G and Open Radio Access Network (O-RAN) architectures expands security risks, increasing both the scale and complexity of mobile network...

Cloud computing environments face persistent structural challenges in cost control, dynamic resource allocation, and security risk management, which traditional infrastructure approaches fail to address adequately. This ...

The sustainable utilization of post-consumer waste glass in concrete has emerged as a promising approach to reduce cement consumption, mitigate landfill disposal, and enhance material performance. However, most previous ...