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IntroductionToday, the rapid acceleration of urbanization has made it necessary to reconsider the balance among energy consumption, environmental sustainability, and quality of life. Buildings, which account for a signif...

Abstract In the present paper we study the relationship between the notions of force, cause and subject of motion in Leibniz’s early dynamics. First, we specify the role that the problem of the subject and cause of mot...

Abstract Background Lung squamous cell carcinoma (LUSC) is one of the common pathological subtypes of non-small cell lung cancer, which poses significant treatment challenges due to poor response to conventional therapie...

Introduction and aims: Increasing evidence suggests that marginal zone B and B1 cell-specific protein (MZB1) plays crucial roles in inflammatory responses, endoplasmic reticulum (ER) stress, and cell survival, but its fu...

Intracellular levels of cyclic nucleotide second messengers are regulated predominantly by a large superfamily of phosphodiesterases (PDEs). Most of the different PDE variants play specific physiological functions; in fa...

Background The well-known ‘pyrotherapy’ of Julius Wagner-Jauregg might be the beginning of the study on the immunological concepts of schizophrenia. As the primary immune effector cells in the brain, microglia play a...

This study integrates a novel multi-beam bathymetry and high-resolution sub-bottom seismic database with previous works, to investigate a Late Quaternary Mixed (turbidite-contourite) Depositional System (MDS) related to ...

Abstract Receptor activator of NF-kB ligand (RANKL) is known to play a major role in bone metabolism and the immune system, and its recombinant form has been expressed in bacterial systems for research since the last two...

Here we present the first use of calcareous microfossils to examine the late Quaternary paleoecology of the endorheic Pozuelos Basin (Argentina). Modern deposition in the basin centers on Laguna de los Pozuelos (LP),a s...

Penelitian ini bertujuan menjelaskan pembinaan karakter dan hambatan penyertaannya dilihat dari teori role taking pada masyarakat "Griya Kota"Tulungagung. Metode penelitian menggunakan pendekatan kualitatif dengan jenis ...

Abstract Background Physical activity (PA) plays a crucial role in the management of Type 2 Diabetes Mellitus (T2DM). Despite its known benefits, many individuals living with T2DM face challenges in maintaining regular P...

Abstract Background Police can play a role in tackling violent extremism through disrupting terrorist plots and by working with communities to identify individuals at risk of radicalisation. Police programmes to tackle v...

Background: An increasing number of Major League Baseball (MLB) pitchers are receiving ulnar collateral ligament reconstruction (UCLR). However, a substantial proportion of pitchers do not regain their preinjury level of...

Combined radiotherapy and chemotherapy remain central to cancer treatment, with metallodrugs – most notably platinum agents – playing indispensable roles in clinical regimens. However, systemic toxicity and limit...

Abstract Small mammals play an essential role in the transmission and maintenance cycles of Borrelia spirochetes. In Chile, recent studies have characterized novel Borrelia genotypes in ticks collected from small mammals...

Apoptosis is a physiological mechanism of programmed cell death, in contrast to necrosis, without eliciting an inflammatory response. It plays the key role in the functioning of different tissues and organs. The balance ...

Embodied and intersubjective experience is crucial to the social cognition processes on which interpersonal relationships are based. We assessed whether promoting these processes through participation in self-awareness a...

Bacteriophages play significant roles in the composition, diversity, and evolution of bacterial communities. Despite their importance, it remains unclear how phage diversity and phage-host interactions are spatially stru...

This article is a reflection on what citizenship means today, how it can be generally characterized, and how it manifests itself in sport. It does not attempt to provide an exhaustive overview of the topic based on a sys...

ABSTRACT Staphylococcus aureus is a common upper respiratory tract (URT) pathobiont with high carriage rates in the upper airway disease chronic rhinosinusitis (CRS). CRS is associated with increased prevalence and abund...

This study aims to see the readiness of each educator in using knowledge-based learning models of technological pedagogic content in Civics learning. In this case, educators and lecturers play an important role in contro...

Abstract China’s engagement in global affairs has changed substantially in the 2010s. One aspect of the country’s global reorientation has been its increased interest in, and willingness to play a role in, global hea...

Abstract Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC) and poses a significant threat to public health. Traditional treatments often lead to poor prognoses and tum...

Background - Plants in over one hundred families in habitats worldwide bear extrafloral nectaries (EFNs). EFNs display a remarkable diversity of evolutionary origins, as well as diverse morphology and location on the pla...