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10 resultados encontrados.

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DSS-PPI: a self-supervised graph learning framework for protein-protein interaction prediction via multimodal sequence semantics
Artículo
Material complementario disponible Artículo DOAJ
DSS-PPI: a self-supervised graph learning framework for protein-protein interaction prediction via multimodal sequence semantics
Shumei Li et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Reliable identification of protein‑protein interactions (PPIs) is crucial for deciphering cellular functional networks. Current research models still face limitations in aligning heterogeneous featu...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Evaluating network-based algorithms for protein function prediction using plant protein-protein interaction networks
Artículo
Material complementario disponible Artículo DOAJ
Evaluating network-based algorithms for protein function prediction using plant protein-protein interaction networks
M. A.S.U. Piyatissa et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Protein-protein interaction (PPI) network-based protein function prediction algorithms, which use the guilt-by-association principle, are widely applied in medical and human domains, but they are comp...
LCC TENDOkJvdGFueQ~~Idioma eng
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Anti-inflammatory and antioxidant effects of Lavandula stoechas L. on human macrophages and in silico prediction of α7 nicotinic acetylcholine receptor interaction
Artículo
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Anti-inflammatory and antioxidant effects of Lavandula stoechas L. on human macrophages and in silico prediction of α7 nicotinic acetylcholine receptor interaction
Elif Baris et al · BMC · 2026 · ISSN 2662-7671
Abstract Background Lavandula stoechas L., commonly known as lavender, has been traditionally used in various therapeutic applications, including as a smoking cessation aid. The aim of this study was to investigate the a...
LCC TENDOk90aGVyIHN5c3RlbXMgb2YgbWVkaWNpbmU~Idioma eng
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Multi-omics prediction of terpene constituents and phenolic traits in Eucalyptus globulus using Bayesian models and tree-based machine learning
Artículo
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Multi-omics prediction of terpene constituents and phenolic traits in Eucalyptus globulus using Bayesian models and tree-based machine learning
Daniel Mieres-Castro et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Terpenes and phenolic compounds are multifunctional plant metabolites that contribute to defense, signaling, and ecological interactions, while supporting industrial applications. Here, we implemented...
LCC TENDOkJvdGFueQ~~Idioma eng
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Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
Artículo
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Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
Ashraf S. A. El-Sayed et al · BMC · 2026 · ISSN 1471-2180
Abstract Epothilone is one of the lead anticancer compounds, with unique binding affinity to the cellular β-tubulin, however, the solubility and efficiency towards the drug-resistant tumors are the challenges. Glutathio...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Impact of germline genetic variation on breast cancer prognosis: a systematic review and meta-analysis
Artículo
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Impact of germline genetic variation on breast cancer prognosis: a systematic review and meta-analysis
Ariadna Gutiérrez-González et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Breast cancer prognosis is the result of complex interactions between tumor biology, treatment, and host factors. While germline genetic variation is increasingly incorporated into breast cancer risk ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
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Interactive effects of telomere length and genetic variants on Alzheimer disease risk across multiple ancestral populations
Artículo
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Interactive effects of telomere length and genetic variants on Alzheimer disease risk across multiple ancestral populations
Zainab Khurshid et al · BMC · 2026 · ISSN 1758-9193
Abstract Background Telomere length (TL), a biomarker of biological aging, but its association with Alzheimer’s disease (AD) remains unclear. Methods We estimated TL in whole-genome sequencing data from 35,014 Alzheime...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng
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Usnic acid induces apoptosis and inhibits cell migration and invasion in hepatocarcinoma cells: in vitro and in silico analysis
Artículo
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Usnic acid induces apoptosis and inhibits cell migration and invasion in hepatocarcinoma cells: in vitro and in silico analysis
Dogukan Mutlu · BMC · 2026 · ISSN 2662-7671
Abstract Background Lichens produce several secondary metabolites with significant biological and pharmacological activities, among which usnic acid (UA) is particularly notable. This study aimed to investigate the cytot...
LCC TENDOk90aGVyIHN5c3RlbXMgb2YgbWVkaWNpbmU~Idioma eng
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Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice
Artículo
Acceso abierto Artículo DOAJ
Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice
Michael Fiorillo et al · BMC · 2026 · ISSN 1471-2202
Abstract Background Neuroinflammation is a hallmark of numerous neuropsychiatric and neurodegenerative disorders. Psychedelics have garnered recent attention for their anti-inflammatory and neuroprotective effects. Howev...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurophysiology and neuropsychologyIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
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Usability study to guide the development of a cognitive behavioral therapy mobile application for reducing irritable bowel syndrome symptoms
Artículo
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Usability study to guide the development of a cognitive behavioral therapy mobile application for reducing irritable bowel syndrome symptoms
Tadahiro Yamazaki et al · BMC · 2026 · ISSN 1751-0759
Abstract Background Irritable bowel syndrome (IBS) is a prevalent disorder of gut-brain interaction in which psychosocial factors can exacerbate symptoms. Although cognitive behavioral therapy (CBT) has proven effective ...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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