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A Comparative Study Between Lipid A Extracted from Salmonella typhi and Pseudomonas Aeruginosa to Demonstrate the Extent of its Stimulation of Immune System

ISSN: 1812125X · Editor / fuente: University of Mosul, College of Education for Pure Science

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Quality of Life in Patients with Severe Combined Immunodeficiency (SCID) Treated with Hematopoietic Cell Transplantation in the Modern Era: A Primary Immune Deficiency Consortium (PIDTC) Study
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Quality of Life in Patients with Severe Combined Immunodeficiency (SCID) Treated with Hematopoietic Cell Transplantation in the Modern Era: A Primary Immune Deficiency Consortium (PIDTC) Study
Lauren Sanchez et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionNewborn screening (NBS) for severe combined immunodeficiency (SCID) leads to early diagnosis and hematopoietic cell transplant (HCT). Limited studies are available on the quality of life (QoL) of SCID patient...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Updated and Initial Validation of Warning Signs: Western Expert-Based Pidcap Delphi Project
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Updated and Initial Validation of Warning Signs: Western Expert-Based Pidcap Delphi Project
Jacques G. Rivière et al · Rockefeller University Press · 2026 · ISSN 3065-8993
ObjectiveEarly recognition of inborn errors of immunity (IEI) is critical to avoid morbidity and irreversible organ damage. Jeffrey Modell Foundation (JMF) warning signs have long guided and still guide clinical suspicio...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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A Whole-Blood Transcriptomic Assay, PrimDx, Reflects Cellular and Humoral Abnormalities in Primary Immunodeficiency
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A Whole-Blood Transcriptomic Assay, PrimDx, Reflects Cellular and Humoral Abnormalities in Primary Immunodeficiency
Holly Pedersen et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Early diagnosis of primary immunodeficiency (PID) remains a significant clinical challenge, often delaying treatment and increasing the risk of severe infections. Accurate identification of antibody (Ab) deficiencies typ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Caregivers of Children with APDS Balance Complex Medical Care, Family, and Work Responsibilities
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Caregivers of Children with APDS Balance Complex Medical Care, Family, and Work Responsibilities
Kristie Cline et al · Rockefeller University Press · 2026 · ISSN 3065-8993
RationaleActivated PI3K delta syndrome (APDS) is a rare primary immunodeficiency disease (PID) characterized in 2013. Caregivers of children with APDS juggle management of complex medical needs with family and work respo...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Clinical Implications of Baseline-Corrected Total Immunoglobulin G Levels: Pharmacokinetic Data from a Phase 3, Open-Label Study of Patients with Primary Immunodeficiency Disease Treated with fSCIG 10%
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Clinical Implications of Baseline-Corrected Total Immunoglobulin G Levels: Pharmacokinetic Data from a Phase 3, Open-Label Study of Patients with Primary Immunodeficiency Disease Treated with fSCIG 10%
Komal Prem et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Dosing immunoglobulin G (IgG) replacement therapy in primary immunodeficiency disease (PIDD) depends on IgG pharmacokinetics (PK) and patients’ clinical status. Conventionally, PK data used to determine dosing were bas...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Enhanced Diagnosis of Primary Immunodeficiencies, Including Bronchiectasis Cases, Using Transcriptomic Artificial Intelligence
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Enhanced Diagnosis of Primary Immunodeficiencies, Including Bronchiectasis Cases, Using Transcriptomic Artificial Intelligence
Benjamin G. Cocks et al · Rockefeller University Press · 2026 · ISSN 3065-8993
This study presents PrimDx, a diagnostic test that applies machine learning (ML) to whole blood transcriptomic data to improve early detection and diagnosis of primary immunodeficiency (PID). Delays in PID diagnosis are ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Expanded Clinical Spectrum Associated with Heterozygous Variants of RNU4ATAC
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Expanded Clinical Spectrum Associated with Heterozygous Variants of RNU4ATAC
Lila Yang et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionRNU4ATAC-opathies are characterized by biallelic pathogenic variants and include three recognized phenotypes: autosomal recessive Roifman syndrome, microcephalic osteodysplastic primordial dwarfism (MOPD), an...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Health-Related Quality of Life (HRQOL) in Pediatric and Adult Patients with X-Linked Hyper IgM
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Health-Related Quality of Life (HRQOL) in Pediatric and Adult Patients with X-Linked Hyper IgM
Hannah Frudden et al · Rockefeller University Press · 2026 · ISSN 3065-8993
BackgroundX-linked hyper IgM syndrome (XHIGM) is a rare primary immunodeficiency (PID) caused by pathogenic variants in the CD40 ligand (CD40LG) gene, resulting in defective immunoglobulin class-switch recombination, cau...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Idiopathic Combined Immunodeficiency Associated with Primary Pulmonary Sporotrichosis
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Idiopathic Combined Immunodeficiency Associated with Primary Pulmonary Sporotrichosis
Marija Rowane et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionSporotrichosis is an uncommon but emerging opportunistic infection in immunocompromised patients. Primary pulmonary sporotrichosis can disseminate and result in significant morbidity and mortality, despite tr...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Impact and Perspectives of Registry-Based Research in Inborn Errors of Immunity/Primary Immune Disorders: Insights from the ESID Registry of 36,681 Patients
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Impact and Perspectives of Registry-Based Research in Inborn Errors of Immunity/Primary Immune Disorders: Insights from the ESID Registry of 36,681 Patients
Markus G. Seidel · Rockefeller University Press · 2026 · ISSN 3065-8993
Clinical research and real-world observational studies are essential for advancing the diagnosis and treatment of rare diseases, such as inborn errors of immunity/primary immune disorders (IEI/PID). To support efficient ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Overlap in Immunologic Pathways Between Asthma and Primary Immunodeficiency Disorders
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Overlap in Immunologic Pathways Between Asthma and Primary Immunodeficiency Disorders
Jooyoung Moon · Rockefeller University Press · 2026 · ISSN 3065-8993
BackgroundAsthma is traditionally conceptualized as a T helper 2 (Th2)-mediated inflammatory airway disease. However, increasing evidence suggests that primary immune dysregulation may underlie or phenotypically mimic as...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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