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Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a survival rate of 4–6 months from diagnosis. PDAC is the fourth leading cause of cancer-related death in the Western world, with a mort...

Abstract Background The therapeutic efficacy of programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) inhibitors in lung cancer management remains suboptimal. Sporoderm-removed Ganoderma Lucidum Spore Pow...

Abstract Background Apoptosis is a fundamental biological process and a central determinant of therapeutic response in breast cancer (BC). Resistance to immunotherapy is increasingly recognized to be driven, in part, by ...

Abstract Epithelial-to-mesenchymal transition (EMT) is a complex and dynamic cellular process during which epithelial cells lose their polarity and cell adhesion capabilities and subsequently express mesenchymal stem cel...

Abstract Background Sodium overload-induced cell death is a novel mode of cell death that differs from other modes and is a very promising new target for cancer therapy. In addition, sodium overload-induced cell death pl...

Abstract Man-made synthetic/manufactured nano-objects (MNOs) are increasingly used in almost every scientific sector, including pharmaceutical, agricultural, food, and drug industries worldwide. Rapid advances in nanotec...